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MIR128A microRNA mir-128a [ Monodelphis domestica (gray short-tailed opossum) ]

Gene ID: 100034334, updated on 8-May-2024

Summary

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Gene symbol
MIR128A
Gene description
microRNA mir-128a
See related
EnsemblRapid:ENSMODG00000022436 miRBase:MI0005293
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Monodelphis domestica
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Didelphimorphia; Didelphidae; Monodelphis
Also known as
MIR128; Mirn128b; mdo-mir-128; mdo-mir-128a; mdo-mir-128b
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

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See MIR128A in Genome Data Viewer
Location:
chromosome: 6
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2023_05 current mMonDom1.pri (GCF_027887165.1) 7 NC_077233.1 (1312548..1312631)
103 previous assembly MonDom5 (GCF_000002295.2) 6 NC_008806.1 (290241098..290241181, complement)

Chromosome 7 - NC_077233.1Genomic Context describing neighboring genes Neighboring gene TAP binding protein like Neighboring gene uncharacterized LOC103092036 Neighboring gene cAMP regulated phosphoprotein 21 Neighboring gene translation initiation factor IF-2-like Neighboring gene uncharacterized LOC103105626

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. In vitro and in silico annotation of conserved and nonconserved microRNAs in the genome of the marsupial Monodelphis domestica. Devor EJ, et al. J Hered, 2008 Jan-Feb. PMID 17965199
  2. Birth and expression evolution of mammalian microRNA genes. Meunier J, et al. Genome Res, 2013 Jan. PMID 23034410, Free PMC Article
  3. miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381832, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Other Names

  • microRNA 128a
  • microRNA 128b
  • microRNA mir-128

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_032169.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    JAQIHD010000013
    Related
    ENSMODT00000028291.2

RefSeqs of Annotated Genomes: GCF_027887165.1-RS_2023_05

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mMonDom1.pri

Genomic

  1. NC_077233.1 Reference mMonDom1.pri

    Range
    1312548..1312631
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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