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CDKN2B cyclin-dependent kinase 2B inhibitor [ Equus caballus (horse) ]

Gene ID: 100034122, updated on 15-Aug-2024

Summary

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Gene symbol
CDKN2B
Gene description
cyclin-dependent kinase 2B inhibitor
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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See CDKN2B in Genome Data Viewer
Location:
chromosome: 23
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_08 current EquCab3.0 (GCF_002863925.1) 23 NC_009166.3 (40699159..40703713, complement)

Chromosome 23 - NC_009166.3Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111770186 Neighboring gene cyclin-dependent kinase 4 inhibitor B Neighboring gene uncharacterized LOC102148466 Neighboring gene DMRT like family A1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_009166.3 Chromosome 23 Reference EquCab3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cyclin-dependent protein serine/threonine kinase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of G1/S transition of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cyclin-dependent protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cyclin-dependent kinase 4 inhibitor B

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009166.3 Reference EquCab3.0 Primary Assembly

    Range
    40699159..40703713 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001496235.5 → XP_001496285.2  cyclin-dependent kinase 4 inhibitor B

    See identical proteins and their annotated locations for XP_001496285.2

    Conserved Domains (3) summary
    cd00204
    Location:24 → 132
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:24 → 110
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:46 → 76
    ANK; ANK repeat [structural motif]
Nucleotide Protein
Heading Accession and Version

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