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PDE3A phosphodiesterase 3A [ Equus caballus (horse) ]

Gene ID: 100034086, updated on 17-Aug-2024

Summary

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Official Symbol
PDE3Aprovided by VGNC
Official Full Name
phosphodiesterase 3Aprovided by VGNC
Primary source
VGNC:VGNC:21243
See related
Ensembl:ENSECAG00000016360
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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See PDE3A in Genome Data Viewer
Location:
chromosome: 6
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_08 current EquCab3.0 (GCF_002863925.1) 6 NC_009149.3 (48266142..48559220)

Chromosome 6 - NC_009149.3Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102148025 Neighboring gene uncharacterized LOC111773938 Neighboring gene solute carrier organic anion transporter family member 1C1-like Neighboring gene solute carrier organic anion transporter family member 1C1 Neighboring gene solute carrier organic anion transporter family member 1B3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_009149.3 Chromosome 6 Reference EquCab3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Potential involvement of EGF-like growth factors and phosphodiesterases in initiation of equine oocyte maturation. Lindbloom SM, et al. Anim Reprod Sci, 2008 Jan 15. PMID 17507186
  2. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cAMP-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cGMP-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in oocyte maturation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of oocyte development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A
Names
phosphodiesterase 3A, cGMP-inhibited
NP_001157449.2
XP_014595949.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001163977.2 → NP_001157449.2  cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A

    Status: PROVISIONAL

    Source sequence(s)
    PJAA01000007
    UniProtKB/TrEMBL
    A0A3Q2GSQ9
    Related
    ENSECAP00000023248.3, ENSECAT00000061202.3
    Conserved Domains (1) summary
    pfam00233
    Location:752 → 1013
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009149.3 Reference EquCab3.0 Primary Assembly

    Range
    48266142..48559220
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014740463.2 → XP_014595949.2  cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A isoform X1

    UniProtKB/TrEMBL
    A0A3Q2GSQ9
    Conserved Domains (1) summary
    pfam00233
    Location:755 → 1016
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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