U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

PLA2G4A phospholipase A2 group IVA [ Equus caballus (horse) ]

Gene ID: 100033889, updated on 17-Aug-2024

Summary

Go to the top of the page Help
Official Symbol
PLA2G4Aprovided by VGNC
Official Full Name
phospholipase A2 group IVAprovided by VGNC
Primary source
VGNC:VGNC:21513
See related
Ensembl:ENSECAG00000024810
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Also known as
PLA2; PLA2G1B
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See PLA2G4A in Genome Data Viewer
Location:
chromosome: 5
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2024_08 current EquCab3.0 (GCF_002863925.1) 5 NC_009148.3 (20629061..20778606)

Chromosome 5 - NC_009148.3Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111773472 Neighboring gene uncharacterized LOC111773383 Neighboring gene CDGSH iron-sulfur domain-containing protein 1 pseudogene Neighboring gene uncharacterized LOC111773384

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_009148.3 Chromosome 5 Reference EquCab3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Endometrial phospholipase A2 activity during the oestrous cycle and early pregnancy in mares. Ababneh MM, et al. Reprod Domest Anim, 2013 Feb. PMID 22486770
  2. Expression of cytosolic phospholipase A2 in equine endometrium during the oestrous cycle and early pregnancy. Ababneh M, et al. Reprod Domest Anim, 2011 Apr. PMID 20626674
  3. Purification, characterization, and cDNA sequencing of cytosolic phospholipase A(2) from equine neutrophils. Forsell PK, et al. J Lipid Res, 2000 Aug. PMID 10946009
  4. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
  5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent phospholipase A2 activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent phospholipid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in glycerophospholipid catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
cytosolic phospholipase A2
Names
cPLA2
phospholipase A2, group IB (pancreas)
phospholipase A2, group IVA (cytosolic, calcium-dependent)
NP_001075312.1
XP_005609795.1
XP_005609796.1
XP_005609797.1
XP_005609799.1
XP_023495977.1
XP_023495978.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081843.1 → NP_001075312.1  cytosolic phospholipase A2

    See identical proteins and their annotated locations for NP_001075312.1

    Status: PROVISIONAL

    Source sequence(s)
    AF092539
    UniProtKB/Swiss-Prot
    O77793
    UniProtKB/TrEMBL
    F6PR02
    Conserved Domains (3) summary
    cd07200
    Location:144 → 730
    cPLA2_Grp-IVA; Group IVA cytosolic phospholipase A2; catalytic domain; Ca-dependent
    cd04036
    Location:20 → 138
    C2_cPLA2; C2 domain present in cytosolic PhosphoLipase A2 (cPLA2)
    smart00022
    Location:117 → 669
    PLAc; Cytoplasmic phospholipase A2, catalytic subunit

RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009148.3 Reference EquCab3.0 Primary Assembly

    Range
    20629061..20778606
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005609738.3 → XP_005609795.1  cytosolic phospholipase A2 isoform X1

    See identical proteins and their annotated locations for XP_005609795.1

    UniProtKB/TrEMBL
    A0A3Q2H7S2, F6PR02
    Related
    ENSECAP00000030001.1, ENSECAT00000064253.3
    Conserved Domains (2) summary
    cd07200
    Location:144 → 730
    cPLA2_Grp-IVA; Group IVA cytosolic phospholipase A2; catalytic domain; Ca-dependent
    cd04036
    Location:20 → 138
    C2_cPLA2; C2 domain present in cytosolic PhosphoLipase A2 (cPLA2)

  2. XM_005609740.3 → XP_005609797.1  cytosolic phospholipase A2 isoform X1

    See identical proteins and their annotated locations for XP_005609797.1

    UniProtKB/TrEMBL
    A0A3Q2H7S2, F6PR02
    Conserved Domains (2) summary
    cd07200
    Location:144 → 730
    cPLA2_Grp-IVA; Group IVA cytosolic phospholipase A2; catalytic domain; Ca-dependent
    cd04036
    Location:20 → 138
    C2_cPLA2; C2 domain present in cytosolic PhosphoLipase A2 (cPLA2)

  3. XM_005609742.3 → XP_005609799.1  cytosolic phospholipase A2 isoform X1

    See identical proteins and their annotated locations for XP_005609799.1

    UniProtKB/TrEMBL
    A0A3Q2H7S2, F6PR02
    Conserved Domains (2) summary
    cd07200
    Location:144 → 730
    cPLA2_Grp-IVA; Group IVA cytosolic phospholipase A2; catalytic domain; Ca-dependent
    cd04036
    Location:20 → 138
    C2_cPLA2; C2 domain present in cytosolic PhosphoLipase A2 (cPLA2)

  4. XM_005609739.3 → XP_005609796.1  cytosolic phospholipase A2 isoform X1

    See identical proteins and their annotated locations for XP_005609796.1

    UniProtKB/TrEMBL
    A0A3Q2H7S2, F6PR02
    Conserved Domains (2) summary
    cd07200
    Location:144 → 730
    cPLA2_Grp-IVA; Group IVA cytosolic phospholipase A2; catalytic domain; Ca-dependent
    cd04036
    Location:20 → 138
    C2_cPLA2; C2 domain present in cytosolic PhosphoLipase A2 (cPLA2)

  5. XM_023640210.1 → XP_023495978.1  cytosolic phospholipase A2 isoform X1

    UniProtKB/TrEMBL
    A0A3Q2H7S2, F6PR02
    Conserved Domains (2) summary
    cd07200
    Location:144 → 730
    cPLA2_Grp-IVA; Group IVA cytosolic phospholipase A2; catalytic domain; Ca-dependent
    cd04036
    Location:20 → 138
    C2_cPLA2; C2 domain present in cytosolic PhosphoLipase A2 (cPLA2)

  6. XM_023640209.1 → XP_023495977.1  cytosolic phospholipase A2 isoform X1

    UniProtKB/TrEMBL
    A0A3Q2H7S2, F6PR02
    Related
    ENSECAP00000022445.2, ENSECAT00000026856.4
    Conserved Domains (2) summary
    cd07200
    Location:144 → 730
    cPLA2_Grp-IVA; Group IVA cytosolic phospholipase A2; catalytic domain; Ca-dependent
    cd04036
    Location:20 → 138
    C2_cPLA2; C2 domain present in cytosolic PhosphoLipase A2 (cPLA2)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O77793.1 GenPept UniProtKB/Swiss-Prot:O77793

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.