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CHRNA1 cholinergic receptor nicotinic alpha 1 subunit [ Monodelphis domestica (gray short-tailed opossum) ]

Gene ID: 100025856, updated on 8-May-2024

Summary

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Gene symbol
CHRNA1
Gene description
cholinergic receptor nicotinic alpha 1 subunit
See related
EnsemblRapid:ENSMODG00000009414
Gene type
protein coding
RefSeq status
MODEL
Organism
Monodelphis domestica
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Didelphimorphia; Didelphidae; Monodelphis
Orthologs
human mouse all
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Genomic context

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See CHRNA1 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2023_05 current mMonDom1.pri (GCF_027887165.1) 4 NC_077230.1 (186342141..186367880, complement)
103 previous assembly MonDom5 (GCF_000002295.2) 4 NC_008804.1 (185746216..185771919, complement)

Chromosome 4 - NC_077230.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103106488 Neighboring gene WAS/WASL interacting protein family member 1 Neighboring gene uncharacterized LOC107649146 Neighboring gene uncharacterized LOC130453719

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables acetylcholine-gated monoatomic cation-selective channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nervous system process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of membrane potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
acetylcholine receptor subunit alpha
Names
cholinergic receptor, nicotinic, alpha 1 (muscle)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_027887165.1-RS_2023_05

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mMonDom1.pri

Genomic

  1. NC_077230.1 Reference mMonDom1.pri

    Range
    186342141..186367880 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001376625.5 → XP_001376662.1  acetylcholine receptor subunit alpha

    UniProtKB/TrEMBL
    A0A5F8H0C0, F7C5D6
    Related
    ENSMODP00000052816.2, ENSMODT00000070940.2
    Conserved Domains (3) summary
    TIGR00860
    Location:21 → 447
    LIC; Cation transporter family protein
    pfam02931
    Location:24 → 231
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
    pfam02932
    Location:238 → 446
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region
Nucleotide Protein
Heading Accession and Version

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