PIK3C3 phosphatidylinositol 3-kinase catalytic subunit type 3 [Monodelphis domestica (gray short-tailed opossum)] - Gene

Summary

Gene symbol: PIK3C3
Gene description: phosphatidylinositol 3-kinase catalytic subunit type 3
See related: EnsemblRapid:ENSMODG00000000219
Gene type: protein coding
RefSeq status: MODEL
Organism: Monodelphis domestica
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Didelphimorphia; Didelphidae; Monodelphis
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
RS_2023_05	current	mMonDom1.pri (GCF_027887165.1)	3	NC_077229.1 (410796151..411012102)
103	previous assembly	MonDom5 (GCF_000002295.2)	3	NC_008803.1 (78433663..78649458, complement)

Chromosome 3 - NC_077229.1 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables 1-phosphatidylinositol-3-kinase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in autophagosome assembly	IEA Inferred from Electronic Annotation more info	PubMed
involved_in autophagy of peroxisome	IEA Inferred from Electronic Annotation more info	PubMed
involved_in endocytosis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in phosphatidylinositol-3-phosphate biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in phosphatidylinositol-mediated signaling	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in endosome	IEA Inferred from Electronic Annotation more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in peroxisome	IEA Inferred from Electronic Annotation more info	PubMed
located_in phagophore assembly site	IEA Inferred from Electronic Annotation more info	PubMed
part_of phosphatidylinositol 3-kinase complex, class III, type I	IEA Inferred from Electronic Annotation more info	PubMed
part_of phosphatidylinositol 3-kinase complex, class III, type II	IEA Inferred from Electronic Annotation more info	PubMed

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The following sections contain reference sequences that belong to a specific genome build. Explain

XM_007486726.3 → XP_007486788.1 phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X1

UniProtKB/TrEMBL

A0A5F8GF03, A0A5F8HG43

Related

ENSMODP00000088971.1, ENSMODT00000094549.1

Conserved Domains (3) summary

cd08397
Location:26 → 186

C2_PI3K_class_III; C2 domain present in class III phosphatidylinositol 3-kinases (PI3Ks)

cd00870
Location:283 → 503

PI3Ka_III; Phosphoinositide 3-kinase (PI3K) class III, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3Ks class III ...

cd00896
Location:539 → 883

PI3Kc_III; Catalytic domain of Class III Phosphoinositide 3-kinase
XM_056824362.1 → XP_056680340.1 phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X2