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acap3b ArfGAP with coiled-coil, ankyrin repeat and PH domains 3b [ Danio rerio (zebrafish) ]

Gene ID: 100009646, updated on 17-Sep-2024

Summary

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Official Symbol
acap3bprovided by ZNC
Official Full Name
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-070209-274
See related
Ensembl:ENSDARG00000099240 AllianceGenome:ZFIN:ZDB-GENE-070209-274
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:158388
Summary
Predicted to enable GTPase activator activity and metal ion binding activity. Orthologous to human ACAP3 (ArfGAP with coiled-coil, ankyrin repeat and PH domains 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See acap3b in Genome Data Viewer
Location:
chromosome: 11
Exon count:
27
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (3385104..3494964, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (3316940..3475577, complement)

Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene sulfite oxidase Neighboring gene microspherule protein 1 Neighboring gene pseudouridine synthase like 1 Neighboring gene DEAD-box helicase 19b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in endosome IEA
Inferred from Electronic Annotation
more info
  
located_in endosome membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001083015.1 → NP_001076484.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3b

    See identical proteins and their annotated locations for NP_001076484.1

    Status: PROVISIONAL

    Source sequence(s)
    BC133093
    UniProtKB/TrEMBL
    A0A0R4IBK3, A2RUY3
    Related
    ENSDARP00000130278.1, ENSDART00000162369.2
    Conserved Domains (7) summary
    cd07637
    Location:16 → 215
    BAR_ACAP3; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with Coiled-coil, ANK repeat and PH domain containing protein 3
    cd00204
    Location:668 → 787
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd13250
    Location:271 → 367
    PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
    pfam00169
    Location:269 → 363
    PH; PH domain
    pfam01412
    Location:403 → 520
    ArfGap; Putative GTPase activating protein for Arf
    pfam12796
    Location:671 → 759
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:666 → 697
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007122.7 Reference GRCz11 Primary Assembly

    Range
    3385104..3494964 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068224075.1 → XP_068080176.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3b isoform X1

Nucleotide Protein
Heading Accession and Version

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