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SERPINE1 serpin family E member 1 [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100009588, updated on 8-Mar-2024

Summary

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Gene symbol
SERPINE1
Gene description
serpin family E member 1
See related
Ensembl:ENSOCUG00000016068
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Also known as
PAI1
Orthologs
human mouse all
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Genomic context

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See SERPINE1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) Unplaced Scaffold NW_026259265.1 (1101746..1109474, complement)

NW_026259265.1Genomic Context describing neighboring genes Neighboring gene VGF nerve growth factor inducible Neighboring gene uncharacterized LOC103345696 Neighboring gene adaptor related protein complex 1 subunit sigma 1 Neighboring gene tripartite motif containing 56 Neighboring gene mucin 17, cell surface associated

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_026259265 Unplaced Scaffold Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Temporal alterations in mRNA levels for proteinases and inhibitors and their potential regulators in the healing medial collateral ligament. Reno C, et al. Biochem Biophys Res Commun, 1998 Nov 27. PMID 9837780
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables serine-type endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of plasminogen activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of vascular wound healing IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
plasminogen activator inhibitor 1
Names
plasminogen activator inhibitor
putative plasminogen activator inhibitor-1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UM_NZW_1.0 Primary Assembly

Genomic

  1. NW_026259265.1 Reference UM_NZW_1.0 Primary Assembly

    Range
    1101746..1109474 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002722823.4 → XP_002722869.1  plasminogen activator inhibitor 1

    UniProtKB/TrEMBL
    G1TAU6
    Related
    ENSOCUP00000013814.3
    Conserved Domains (1) summary
    cl00137
    Location:27 → 401
    SERPIN; SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate ...
Nucleotide Protein
Heading Accession and Version

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