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SOD3 superoxide dismutase 3 [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100009320, updated on 8-Mar-2024

Summary

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Gene symbol
SOD3
Gene description
superoxide dismutase 3
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
human mouse all
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Genomic context

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See SOD3 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 2 NC_067375.1 (15911050..15918107)

Chromosome 2 - NC_067375.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L37a Neighboring gene uncharacterized LOC127490358 Neighboring gene coiled-coil domain containing 149 Neighboring gene leucine rich repeat LGI family member 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_067375.1 Chromosome 2 Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Extracellular superoxide dismutase is a growth regulatory mediator of tissue injury recovery. Laurila JP, et al. Mol Ther, 2009 Mar. PMID 19107121, Free PMC Article
  2. Rabbit extracellular superoxide dismutase: expression and effect on LDL oxidation. Laukkanen MO, et al. Gene, 2000 Aug 22. PMID 10974548
  3. Local hypomethylation in atherosclerosis found in rabbit ec-sod gene. Laukkanen MO, et al. Arterioscler Thromb Vasc Biol, 1999 Sep. PMID 10479660
  4. Induction of 15-lipoxygenase mRNA and protein in early atherosclerotic lesions. Hiltunen T, et al. Circulation, 1995 Dec 1. PMID 7586317
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. suggests a new physiological role for SOD3 as a Ras regulatory molecule in signal transduction
    Title: Extracellular superoxide dismutase is a growth regulatory mediator of tissue injury recovery.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables copper ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables superoxide dismutase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in removal of superoxide radicals IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
extracellular superoxide dismutase [Cu-Zn]
Names
EC-SOD
Extracellular superoxide dismutase
superoxide dismutase 3, extracellular
NP_001076101.1
XP_051684739.1
XP_051684750.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001082632.1 → NP_001076101.1  extracellular superoxide dismutase [Cu-Zn] precursor

    See identical proteins and their annotated locations for NP_001076101.1

    Status: PROVISIONAL

    Source sequence(s)
    Z67878
    UniProtKB/Swiss-Prot
    P41975
    Conserved Domains (1) summary
    pfam00080
    Location:82 → 214
    Sod_Cu; Copper/zinc superoxide dismutase (SODC)

RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UM_NZW_1.0 Primary Assembly

Genomic

  1. NC_067375.1 Reference UM_NZW_1.0 Primary Assembly

    Range
    15911050..15918107
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_051828779.1 → XP_051684739.1  extracellular superoxide dismutase [Cu-Zn] isoform X1

    UniProtKB/Swiss-Prot
    P41975

  2. XM_051828790.1 → XP_051684750.1  extracellular superoxide dismutase [Cu-Zn] isoform X1

    UniProtKB/Swiss-Prot
    P41975
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P41975.2 GenPept UniProtKB/Swiss-Prot:P41975

Gene LinkOut

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