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PLB1 phospholipase B1 [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100009309, updated on 10-Oct-2024

Summary

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Gene symbol
PLB1
Gene description
phospholipase B1
See related
Ensembl:ENSOCUG00000015168
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Also known as
PHLPB
Orthologs
human mouse all
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Genomic context

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See PLB1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
61
Annotation release Status Assembly Chr Location
RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 2 NC_067375.1 (157735626..157860182, complement)

Chromosome 2 - NC_067375.1Genomic Context describing neighboring genes Neighboring gene speedy/RINGO cell cycle regulator family member A Neighboring gene protein phosphatase 1 catalytic subunit beta Neighboring gene uncharacterized LOC127490347 Neighboring gene FOS like 2, AP-1 transcription factor subunit Neighboring gene uncharacterized LOC127490379 Neighboring gene BRISC and BRCA1 A complex member 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_067375.1 Chromosome 2 Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Messenger RNAs expressed in intestine of adult but not baby rabbits. Isolation of cognate cDNAs and characterization of a novel brush border protein with esterase and phospholipase activity. Boll W, et al. J Biol Chem, 1993 Jun 15. PMID 8509424
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phospholipase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in phospholipid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phospholipase B1, membrane-associated
Names
PLB/LIP
lysophospholipase
phospholipase A2
phospholipase AdRab-B
phospholipase B
phospholipase B/lipase
triacylglycerol lipase
NP_001095178.1
XP_051684699.1
XP_051684705.1
XP_051684714.1
XP_051684721.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001101708.1 → NP_001095178.1  phospholipase B1, membrane-associated precursor

    See identical proteins and their annotated locations for NP_001095178.1

    Status: PROVISIONAL

    Source sequence(s)
    Z12841
    UniProtKB/Swiss-Prot
    Q05017
    UniProtKB/TrEMBL
    G1T8Y1
    Related
    ENSOCUP00000013064.4, ENSOCUT00000015201.4
    Conserved Domains (2) summary
    cd01824
    Location:382 → 677
    Phospholipase_B_like; Phospholipase-B_like. This subgroup of the SGNH-family of lipolytic enzymes may have both esterase and phospholipase-A/lysophospholipase activity. It's members may be involved in the conversion of phosphatidylcholine to fatty acids and ...
    cl01053
    Location:61 → 317
    SGNH_hydrolase; SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely ...

RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UM_NZW_1.0 Primary Assembly

Genomic

  1. NC_067375.1 Reference UM_NZW_1.0 Primary Assembly

    Range
    157735626..157860182 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_051828745.1 → XP_051684705.1  phospholipase B1, membrane-associated isoform X2

  2. XM_051828754.1 → XP_051684714.1  phospholipase B1, membrane-associated isoform X3

  3. XM_051828739.1 → XP_051684699.1  phospholipase B1, membrane-associated isoform X1

  4. XM_051828761.1 → XP_051684721.1  phospholipase B1, membrane-associated isoform X4

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q05017.1 GenPept UniProtKB/Swiss-Prot:Q05017

Gene LinkOut

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