PPP2CA protein phosphatase 2 catalytic subunit alpha [Oryctolagus cuniculus (rabbit)] - Gene

Summary

Gene symbol: PPP2CA
Gene description: protein phosphatase 2 catalytic subunit alpha
See related: Ensembl:ENSOCUG00000015961
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Oryctolagus cuniculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Annotation information: Annotation category: partial on reference assembly
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2023_02	current	UM_NZW_1.0 (GCF_009806435.1)	3	NC_067376.1 (16958768..17007442, complement)

Chromosome 3 - NC_067376.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_067376.1 Chromosome 3 Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phosphoprotein Phosphatase 1 but Not 2A Activity Modulates Coupled-Clock Mechanisms to Impact on Intrinsic Automaticity of Sinoatrial Nodal Pacemaker Cells.
Title: Phosphoprotein Phosphatase 1 but Not 2A Activity Modulates Coupled-Clock Mechanisms to Impact on Intrinsic Automaticity of Sinoatrial Nodal Pacemaker Cells.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Ppp2ca (e-PCR), detects polymorphism
- UniSTS:526870

Ppp2ca (e-PCR), detects polymorphism
- UniSTS:526871

PMC22838P1 (e-PCR)
- UniSTS:272153

D5S2786 (e-PCR)
- UniSTS:473854

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein serine/threonine phosphatase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in mitotic cell cycle	IEA Inferred from Electronic Annotation more info	PubMed
involved_in peptidyl-serine dephosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

Names: PP2A-alpha; protein phosphatase 2, catalytic subunit, alpha isozyme

NP_001095156.1

EC 3.1.3.16

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001101686.1 → NP_001095156.1 serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

See identical proteins and their annotated locations for NP_001095156.1

Status: PROVISIONAL

Source sequence(s)

X06087

UniProtKB/Swiss-Prot

P67777

UniProtKB/TrEMBL

A0A5F9DM35

Related

ENSOCUP00000013713.2, ENSOCUT00000015956.4

Conserved Domains (1) summary

cd07415
Location:9 → 293

MPP_PP2A_PP4_PP6; PP2A, PP4, and PP6 phosphoprotein phosphatases, metallophosphatase domain