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PNLIP pancreatic lipase [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100009157, updated on 9-Nov-2023

Summary

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Gene symbol
PNLIP
Gene description
pancreatic lipase
See related
Ensembl:ENSOCUG00000029602
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Also known as
PTL; PNLIPRP2
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Genomic context

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See PNLIP in Genome Data Viewer
Location:
chromosome: 18
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 18 NC_067391.1 (61007515..61026263)

Chromosome 18 - NC_067391.1Genomic Context describing neighboring genes Neighboring gene pancreatic triacylglycerol lipase Neighboring gene uncharacterized LOC103351432 Neighboring gene pancreatic triacylglycerol lipase-like Neighboring gene pancreatic lipase related protein 1 Neighboring gene uncharacterized LOC127484302

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_067391.1 Chromosome 18 Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular cloning and characterization of rabbit pancreatic triglyceride lipase. Aleman-Gomez JA, et al. Biochem Biophys Res Commun, 1992 Nov 16. PMID 1445366

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables triglyceride lipase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
pancreatic triacylglycerol lipase
Names
PL
triglyceride lipase
NP_001075786.1
XP_008268675.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001082317.1 → NP_001075786.1  pancreatic triacylglycerol lipase precursor

    See identical proteins and their annotated locations for NP_001075786.1

    Status: PROVISIONAL

    Source sequence(s)
    M99365
    UniProtKB/Swiss-Prot
    Q02157
    UniProtKB/TrEMBL
    A0A5F9C5N6
    Related
    ENSOCUP00000012518.4, ENSOCUT00000014561.4
    Conserved Domains (3) summary
    cd00707
    Location:52 → 348
    Pancreat_lipase_like; Pancreatic lipase-like enzymes. Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the ...
    cd01759
    Location:355 → 465
    PLAT_PL; PLAT/LH2 domain of pancreatic triglyceride lipase. Lipases hydrolyze phospholipids and triglycerides to generate fatty acids for energy production or for storage and to release inositol phosphates that act as second messengers. The central role of ...
    pfam00151
    Location:18 → 352
    Lipase; Lipase

RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UM_NZW_1.0 Primary Assembly

Genomic

  1. NC_067391.1 Reference UM_NZW_1.0 Primary Assembly

    Range
    61007515..61026263
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008270453.3 → XP_008268675.1  pancreatic triacylglycerol lipase isoform X1

    UniProtKB/TrEMBL
    A0A5F9C5N6, G1T7N2
    Conserved Domains (3) summary
    cd00707
    Location:51 → 348
    Pancreat_lipase_like; Pancreatic lipase-like enzymes. Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the ...
    cd01759
    Location:355 → 465
    PLAT_PL; PLAT/LH2 domain of pancreatic triglyceride lipase. Lipases hydrolyze phospholipids and triglycerides to generate fatty acids for energy production or for storage and to release inositol phosphates that act as second messengers. The central role of ...
    pfam00151
    Location:18 → 352
    Lipase; Lipase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q02157.1 GenPept UniProtKB/Swiss-Prot:Q02157

Gene LinkOut

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