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COL1A2 collagen type I alpha 2 chain [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100008997, updated on 8-Mar-2024

Summary

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Gene symbol
COL1A2
Gene description
collagen type I alpha 2 chain
See related
Ensembl:ENSOCUG00000012264
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
human mouse all
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Genomic context

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See COL1A2 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
52
Annotation release Status Assembly Chr Location
RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 10 NC_067383.1 (31505581..31541365, complement)

Chromosome 10 - NC_067383.1Genomic Context describing neighboring genes Neighboring gene sarcoglycan epsilon Neighboring gene CAS1 domain containing 1 Neighboring gene elongation factor 1-alpha 1-like Neighboring gene uncharacterized LOC127492627

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_067383.1 Chromosome 10 Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Vascular adventitial cell expression of collagen I messenger ribonucleic acid in anti-glomerular basement membrane antibody-induced crescentic nephritis in the rabbit. A cellular source for interstitial collagen synthesis in inflammatory renal disease. Wiggins R, et al. Lab Invest, 1993 May. PMID 8497127
  2. Increased ferritin gene expression is both promoted by cAMP and a marker of growth arrest in rabbit vascular smooth muscle cells. Liau G, et al. J Biol Chem, 1991 Oct 5. PMID 1655764
  3. PDI-mediated ER retention and proteasomal degradation of procollagen I in corneal endothelial cells. Ko MK, et al. Exp Cell Res, 2004 Apr 15. PMID 15051487
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables extracellular matrix structural constituent IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of collagen type I trimer IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
collagen alpha-2(I) chain
Names
alpha 2(I) procollagen
alpha-2 type I collagen
collagen I alpha-2 polypeptide
collagen, type I, alpha 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001195668.1 → NP_001182597.1  collagen alpha-2(I) chain precursor

    Status: PROVISIONAL

    Source sequence(s)
    VIYN02002999
    UniProtKB/TrEMBL
    G1T2Z5
    Related
    ENSOCUP00000010575.2, ENSOCUT00000012284.4
    Conserved Domains (2) summary
    pfam01391
    Location:542 → 601
    Collagen; Collagen triple helix repeat (20 copies)
    pfam01410
    Location:1132 → 1363
    COLFI; Fibrillar collagen C-terminal domain

RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UM_NZW_1.0 Primary Assembly

Genomic

  1. NC_067383.1 Reference UM_NZW_1.0 Primary Assembly

    Range
    31505581..31541365 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q28668.1 GenPept UniProtKB/Swiss-Prot:Q28668

Gene LinkOut

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