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SCP2 sterol carrier protein 2 [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100008683, updated on 8-Mar-2024

Summary

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Gene symbol
SCP2
Gene description
sterol carrier protein 2
See related
Ensembl:ENSOCUG00000002555
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
human mouse all
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Genomic context

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See SCP2 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 13 NC_067386.1 (113824301..113927254, complement)

Chromosome 13 - NC_067386.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 1 member 7 Neighboring gene podocan Neighboring gene enoyl-CoA hydratase domain containing 2 Neighboring gene zyg-11 family member A, cell cycle regulator

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_067386.1 Chromosome 13 Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structure of sterol carrier protein 2 at 1.8 A resolution reveals a hydrophobic tunnel suitable for lipid binding. Choinowski T, et al. Biochemistry, 2000 Feb 29. PMID 10684638
  2. Crystallization and initial X-ray analysis of rabbit mature sterol carrier protein 2. Choinowski T, et al. Acta Crystallogr D Biol Crystallogr, 1999 Aug. PMID 10417421
  3. In pre-sterol carrier protein 2 (SCP2) in solution the leader peptide 1-20 is flexibly disordered, and residues 21-143 adopt the same globular fold as in mature SCP2. Weber FE, et al. Cell Mol Life Sci, 1998 Jul. PMID 9711242, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables acyltransferase activity, transferring groups other than amino-acyl groups IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sterol carrier protein 2
Names
NSL-TP
SCP-2
SCP-2/3-oxoacyl-CoA thiolase
SCP-2/thiolase
SCP-X
SCP-chi
SCPX
acetyl-CoA C-myristoyltransferase
non-specific lipid-transfer protein
propanoyl-CoA C-acyltransferase
sterol carrier protein X
NP_001075504.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001082035.1 → NP_001075504.1  sterol carrier protein 2

    Status: PROVISIONAL

    Source sequence(s)
    AF051897
    UniProtKB/Swiss-Prot
    O62742
    UniProtKB/TrEMBL
    G1TS13
    Related
    ENSOCUP00000019823.3, ENSOCUT00000023566.3
    Conserved Domains (3) summary
    PRK08256
    Location:13 → 404
    PRK08256; lipid-transfer protein; Provisional
    cd00826
    Location:17 → 403
    nondecarbox_cond_enzymes; nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. There are 2 ...
    pfam02036
    Location:452 → 538
    SCP2; SCP-2 sterol transfer family

RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UM_NZW_1.0 Primary Assembly

Genomic

  1. NC_067386.1 Reference UM_NZW_1.0 Primary Assembly

    Range
    113824301..113927254 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O62742.1 GenPept UniProtKB/Swiss-Prot:O62742

Gene LinkOut

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