CLIC6 chloride intracellular channel 6 [Oryctolagus cuniculus (rabbit)] - Gene

Summary

Gene symbol: CLIC6
Gene description: chloride intracellular channel 6
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Oryctolagus cuniculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: Un

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2023_02	current	UM_NZW_1.0 (GCF_009806435.1)	Unplaced Scaffold	NW_026259175.1 (4675038..4720958, complement)

NW_026259175.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NW_026259175 Unplaced Scaffold Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables D2 dopamine receptor binding	IEA Inferred from Electronic Annotation more info	PubMed
enables D3 dopamine receptor binding	IEA Inferred from Electronic Annotation more info	PubMed
enables D4 dopamine receptor binding	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: chloride intracellular channel protein 6

Names: glutaredoxin-like oxidoreductase CLIC6; parchorin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001082004.1 → NP_001075473.1 chloride intracellular channel protein 6

See identical proteins and their annotated locations for NP_001075473.1

Status: PROVISIONAL

Source sequence(s)

AB035520

UniProtKB/Swiss-Prot

Q9N2G5

Conserved Domains (5) summary

TIGR00862
Location:404 → 637

O-ClC; intracellular chloride channel protein

cd03061
Location:401 → 489

GST_N_CLIC; GST_N family, Chloride Intracellular Channel (CLIC) subfamily; composed of CLIC1-5, p64, parchorin and similar proteins. They are auto-inserting, self-assembling intracellular anion channels involved in a wide variety of functions including regulated ...

pfam15724
Location:300 → 382

TMEM119; TMEM119 family

cl02776
Location:496 → 635

GST_C_family; C-terminal, alpha helical domain of the Glutathione S-transferase family

cl19219
Location:153 → 238

DUF342; Protein of unknown function (DUF342)