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ora2 olfactory receptor class A related 2 [ Danio rerio (zebrafish) ]

Gene ID: 100005331, updated on 2-Nov-2024

Summary

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Official Symbol
ora2provided by ZNC
Official Full Name
olfactory receptor class A related 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-070622-3
See related
AllianceGenome:ZFIN:ZDB-GENE-070622-3
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
v1r1
Summary
Predicted to enable pheromone receptor activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and response to pheromone. Located in plasma membrane. Is expressed in female organism; male organism; olfactory epithelium; and olfactory rosette. [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

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See ora2 in Genome Data Viewer
Location:
chromosome: 22
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (211172..214629)

Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene rootletin-like Neighboring gene F-box protein 42 Neighboring gene olfactory receptor class A-like protein 1 Neighboring gene olfactory receptor class A related 1 Neighboring gene zgc:66156 Neighboring gene uncharacterized LOC137488988

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_007133.7 Chromosome 22 Reference GRCz11 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ORA1, a zebrafish olfactory receptor ancestral to all mammalian V1R genes, recognizes 4-hydroxyphenylacetic acid, a putative reproductive pheromone. Behrens M, et al. J Biol Chem, 2014 Jul 11. PMID 24831010, Free PMC Article
  2. Divergent evolution among teleost V1r receptor genes. Pfister P, et al. PLoS One, 2007 Apr 18. PMID 17440615, Free PMC Article
  3. Spatial organization of olfactory receptor gene choice in the complete V1R-related ORA family of zebrafish. Kowatschew D, et al. Sci Rep, 2022 Aug 31. PMID 36045218, Free PMC Article
  4. A novel olfactory receptor gene family in teleost fish. Saraiva LR, et al. Genome Res, 2007 Oct. PMID 17717047, Free PMC Article
  5. Two highly related odorant receptors specifically detect α-bile acid pheromones in sea lamprey (Petromyzon marinus). Zhang Z, et al. J Biol Chem, 2020 Aug 21. PMID 32636305, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables pheromone receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables pheromone receptor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within response to pheromone IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
olfactory receptor class A related 2
Names
V1R pheromone receptor-like protein
olfactory receptor class A (V1r-like homolog)
vn1r1l

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001098395.1 → NP_001091865.1  olfactory receptor class A related 2

    See identical proteins and their annotated locations for NP_001091865.1

    Status: PROVISIONAL

    Source sequence(s)
    DQ887614
    UniProtKB/TrEMBL
    A5H1X0
    Conserved Domains (1) summary
    pfam03402
    Location:37 → 289
    V1R; Vomeronasal organ pheromone receptor family, V1R

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007133.7 Reference GRCz11 Primary Assembly

    Range
    211172..214629
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068216191.1 → XP_068072292.1  olfactory receptor class A related 2 isoform X1

Nucleotide Protein Strain
Heading Accession and Version

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