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zgc:162872 zgc:162872 [ Danio rerio (zebrafish) ]

Gene ID: 100004931, updated on 12-Sep-2024

Summary

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Official Symbol
zgc:162872provided by ZNC
Official Full Name
zgc:162872provided by ZNC
Primary source
ZFIN:ZDB-GENE-081022-1
See related
Ensembl:ENSDARG00000012184 AllianceGenome:ZFIN:ZDB-GENE-081022-1
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable GTPase activator activity and metal ion binding activity. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See zgc:162872 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (46678979..46718781, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (46445281..46484604, complement)

Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene coagulation factor IX Neighboring gene interacts with SUPT6H, CTD assembly factor 1 Neighboring gene integrin-linked kinase-associated serine/threonine phosphatase Neighboring gene transfer RNA glycine (anticodon UCC)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC162872

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in endosome IEA
Inferred from Electronic Annotation
more info
  
located_in endosome membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
BAR_ACAPs and ArfGap_ACAP domain-containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001098194.1 → NP_001091664.1  BAR_ACAPs and ArfGap_ACAP domain-containing protein

    See identical proteins and their annotated locations for NP_001091664.1

    Status: PROVISIONAL

    Source sequence(s)
    BC139884
    UniProtKB/TrEMBL
    A5D6U1
    Related
    ENSDARP00000080361.2, ENSDART00000085926.4
    Conserved Domains (7) summary
    cd07603
    Location:18 → 217
    BAR_ACAPs; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with Coiled-coil, ANK repeat and PH domain containing proteins
    cd00204
    Location:522 → 599
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd13250
    Location:266 → 362
    PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
    pfam00169
    Location:265 → 357
    PH; PH domain
    pfam01412
    Location:399 → 504
    ArfGap; Putative GTPase activating protein for Arf
    pfam13857
    Location:538 → 593
    Ank_5; Ankyrin repeats (many copies)
    sd00045
    Location:550 → 583
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007126.7 Reference GRCz11 Primary Assembly

    Range
    46678979..46718781 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021481318.2 → XP_021336993.1  BAR_ACAPs and ArfGap_ACAP domain-containing protein isoform X2

    UniProtKB/TrEMBL
    A0A8M9QBT1
    Conserved Domains (5) summary
    cd07603
    Location:18 → 176
    BAR_ACAPs; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with Coiled-coil, ANK repeat and PH domain containing proteins
    cd00204
    Location:450 → 566
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd13250
    Location:194 → 290
    PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
    sd00045
    Location:480 → 511
    ANK; ANK repeat [structural motif]
    pfam01412
    Location:327 → 432
    ArfGap; Putative GTPase activating protein for Arf

  2. XM_009291987.4 → XP_009290262.1  BAR_ACAPs and ArfGap_ACAP domain-containing protein isoform X1

    UniProtKB/TrEMBL
    A0A8M3AHR8
    Conserved Domains (7) summary
    cd07603
    Location:18 → 217
    BAR_ACAPs; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with Coiled-coil, ANK repeat and PH domain containing proteins
    cd00204
    Location:522 → 638
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd13250
    Location:266 → 362
    PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
    pfam00169
    Location:265 → 357
    PH; PH domain
    pfam01412
    Location:399 → 504
    ArfGap; Putative GTPase activating protein for Arf
    pfam12796
    Location:557 → 649
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:552 → 583
    ANK; ANK repeat [structural motif]
Nucleotide Protein Strain
Heading Accession and Version

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