trmt61b tRNA methyltransferase 61B [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: trmt61bprovided by ZNC
Official Full Name: tRNA methyltransferase 61Bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-131127-35
See related: Ensembl:ENSDARG00000097465 AllianceGenome:ZFIN:ZDB-GENE-131127-35
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: si:dkey-74h17.5
Summary: Predicted to enable tRNA (adenine-N1-)-methyltransferase activity. Predicted to be involved in mitochondrial tRNA methylation. Predicted to act upstream of or within methylation. Predicted to be part of tRNA (m1A) methyltransferase complex. Predicted to be active in mitochondrion. Orthologous to human TRMT61B (tRNA methyltransferase 61B). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 17

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	17	NC_007128.7 (24815217..24820753, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	17	NC_007128.6 (24796816..24802352, complement)

Chromosome 17 - NC_007128.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables tRNA (adenine(58)-N1)-methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within methylation	IEA Inferred from Electronic Annotation more info
involved_in tRNA methylation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within tRNA methylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within tRNA processing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
part_of tRNA (m1A) methyltransferase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of tRNA (m1A) methyltransferase complex	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial

Names: tRNA methyltransferase 61 homolog B

NP_001314862.1

EC 2.1.1.220

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001327933.1 → NP_001314862.1 tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial

Status: VALIDATED

Source sequence(s)

CR388164, EH491423, EH517758

UniProtKB/TrEMBL

A0A8M1P392, X1WF30

Related

ENSDARP00000128834.1, ENSDART00000156606.3

Conserved Domains (2) summary

COG2519
Location:153 → 448

Gcd14; tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]

cl17173
Location:215 → 442

AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...