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tafa5a TAFA chemokine like family member 5a [ Danio rerio (zebrafish) ]

Gene ID: 100002919, updated on 2-Nov-2024

Summary

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Official Symbol
tafa5aprovided by ZNC
Official Full Name
TAFA chemokine like family member 5aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-041210-344
See related
Ensembl:ENSDARG00000069160 AllianceGenome:ZFIN:ZDB-GENE-041210-344
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
sam5a; fam19a5; fam19a5a; si:dkey-200m9.1; si:dkey-27f18.1; si:dkey-164m14.8
Summary
Predicted to enable G protein-coupled receptor binding activity and receptor ligand activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in extracellular space. Is expressed in brain. Orthologous to human TAFA5 (TAFA chemokine like family member 5). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See tafa5a in Genome Data Viewer
Location:
chromosome: 4
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (27251865..27399210, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (27262231..27409906, complement)

Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene bromodomain containing 1a Neighboring gene uncharacterized LOC137491561 Neighboring gene TBC1 domain family, member 22a Neighboring gene ceramide kinase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. FAM19A5l Affects Mustard Oil-Induced Peripheral Nociception in Zebrafish. Jeong I, et al. Mol Neurobiol, 2021 Sep. PMID 34176096
  2. Targeted knockout of a chemokine-like gene increases anxiety and fear responses. Choi JH, et al. Proc Natl Acad Sci U S A, 2018 Jan 30. PMID 29339520, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables G protein-coupled receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables receptor ligand activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
chemokine-like protein TAFA-5a
Names
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5a
family with sequence similarity 19 member A5, C-C motif chemokine like a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001430368.1 → NP_001417297.1  chemokine-like protein TAFA-5a isoform 1

    Status: VALIDATED

    Source sequence(s)
    BX649406, BX901914, CR751234
    UniProtKB/TrEMBL
    A0A2R8QIB8, A0A8M2BFW6
    Related
    ENSDARP00000125559.1, ENSDART00000142117.4

  2. NM_001430369.1 → NP_001417298.1  chemokine-like protein TAFA-5a isoform 2

    Status: VALIDATED

    Source sequence(s)
    BX901914, CR751234
    UniProtKB/TrEMBL
    A0A8M2BGH3

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007115.7 Reference GRCz11 Primary Assembly

    Range
    27251865..27399210 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005168536.5 → XP_005168593.1  chemokine-like protein TAFA-5a isoform X1

    UniProtKB/TrEMBL
    A0A8M2BFV2, H0WEJ8
    Related
    ENSDARP00000125276.1, ENSDART00000150553.2
    Conserved Domains (1) summary
    pfam12020
    Location:42 → 131
    TAFA; TAFA family

  2. XM_005168537.5 → XP_005168594.1  chemokine-like protein TAFA-5a isoform X2

    UniProtKB/TrEMBL
    A0A8M2BFV3, A2BIC8
    Related
    ENSDARP00000114783.1, ENSDART00000145806.3
    Conserved Domains (1) summary
    pfam12020
    Location:41 → 130
    TAFA; TAFA family

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394558.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    201697..300731 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001122744.1: Suppressed sequence

    Description
    NM_001122744.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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