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hivep1 HIVEP zinc finger 1 [ Danio rerio (zebrafish) ]

Gene ID: 100000517, updated on 2-Nov-2024

Summary

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Official Symbol
hivep1provided by ZNC
Official Full Name
HIVEP zinc finger 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-070912-512
See related
Ensembl:ENSDARG00000103658 AllianceGenome:ZFIN:ZDB-GENE-070912-512
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dkey-31k9.2; si:dkey-184j23.2
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human HIVEP1 (HIVEP zinc finger 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See hivep1 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (3386138..3488484, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (3445244..3502711, complement)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene si:ch211-133n4.9 Neighboring gene endothelin 1 Neighboring gene uncharacterized LOC137488459 Neighboring gene transmembrane protein 170B Neighboring gene uncharacterized LOC137488460

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. HIVEP1 Is a Negative Regulator of NF-κB That Inhibits Systemic Inflammation in Sepsis. Matsumoto H, et al. Front Immunol, 2021. PMID 34804025, Free PMC Article
  2. The endothelin system: evolution of vertebrate-specific ligand-receptor interactions by three rounds of genome duplication. Braasch I, et al. Mol Biol Evol, 2009 Apr. PMID 19174480
  3. Endocardial identity is established during early somitogenesis by Bmp signalling acting upstream of npas4l and etv2. Capon SJ, et al. Development, 2022 May 1. PMID 35531980, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger protein 40
Names
human immunodeficiency virus type I enhancer binding protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    3386138..3488484 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021468249.2 → XP_021323924.1  zinc finger protein 40 isoform X2

    UniProtKB/TrEMBL
    A0A0R4IKT3, A0A8M9PS66
    Related
    ENSDARP00000136567.1, ENSDART00000172520.2
    Conserved Domains (6) summary
    sd00017
    Location:352 → 372
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:1994 → 2014
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:1992 → 2014
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:365 → 389
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:2020 → 2046
    zf-H2C2_5; C2H2-type zinc-finger domain
    cl25496
    Location:2110 → 2410
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

  2. XM_021468250.2 → XP_021323925.1  zinc finger protein 40 isoform X2

    UniProtKB/TrEMBL
    A0A0R4IKT3, A0A8M9PS66
    Conserved Domains (6) summary
    sd00017
    Location:352 → 372
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:1994 → 2014
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:1992 → 2014
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:365 → 389
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:2020 → 2046
    zf-H2C2_5; C2H2-type zinc-finger domain
    cl25496
    Location:2110 → 2410
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

  3. XM_021468251.2 → XP_021323926.1  zinc finger protein 40 isoform X4

    UniProtKB/TrEMBL
    A0A8M9PNW6
    Related
    ENSDARP00000136102.1, ENSDART00000168139.2
    Conserved Domains (6) summary
    sd00017
    Location:354 → 374
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:1996 → 2016
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:1994 → 2016
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:367 → 391
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:2022 → 2048
    zf-H2C2_5; C2H2-type zinc-finger domain
    cl25496
    Location:2110 → 2247
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

  4. XM_021468248.2 → XP_021323923.1  zinc finger protein 40 isoform X1

    UniProtKB/TrEMBL
    A0A8M9PBC6
    Conserved Domains (6) summary
    sd00017
    Location:354 → 374
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:1996 → 2016
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:1994 → 2016
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:367 → 391
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:2022 → 2048
    zf-H2C2_5; C2H2-type zinc-finger domain
    cl25496
    Location:2112 → 2412
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

  5. XM_009293969.4 → XP_009292244.1  zinc finger protein 40 isoform X3

    See identical proteins and their annotated locations for XP_009292244.1

    UniProtKB/TrEMBL
    A0A8M3AV90
    Conserved Domains (4) summary
    sd00017
    Location:175 → 195
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:1817 → 1837
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:1815 → 1837
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:188 → 212
    zf-H2C2_2; Zinc-finger double domain

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018395050.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    36412..42873 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_002457554.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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