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Links from GEO DataSets

Items: 20

1.

Mouse Expression DB 2001 CHMC

(Submitter supplied) Expression profiles of different mouse tissue samples profiles. Keywords: other
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1406
161 Samples
Download data
Series
Accession:
GSE2178
ID:
200002178
2.

Spinal cord and dorsal root ganglion gene expression

(Submitter supplied) We used microarrays to test the fundamental quantitative differences between central and peripheral nervous system transcriptomes. Keywords: repeat
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS2209
Platform:
GPL1261
6 Samples
Download data
Series
Accession:
GSE5425
ID:
200005425
3.
Full record GDS2209

Spinal cord and dorsal root ganglion

Analysis of spinal cord (SC) and dorsal root ganglion (DRG). The central nervous system (CNS) comprises the brain and SC; the peripheral nervous system (PNS) includes spinal and cranial nerves along with their associated DRGs. Results identify gene expression differences between the CNS and the PNS.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 tissue sets
Platform:
GPL1261
Series:
GSE5425
6 Samples
Download data
DataSet
Accession:
GDS2209
ID:
2209
4.

Laser microdissection and microarray analysis of the hippocampus of Rasgrf1 knockout mice

(Submitter supplied) We used manual macrodissection or laser capture microdissection (LCM) to isolate tissue sections of the hippocampus area of Ras-GRF1 wild type and knockout mice brains, and analyzed their transcriptional patterns using commercial oligonucleotide microarrays. Comparison between the transcriptomes of macrodissected and microdissected samples showed that the LCM samples allowed detection of significantly higher numbers of differentially expressed genes, with higher statistical rates of significance. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS2816
Platform:
GPL339
6 Samples
Download data: CEL, CHP
Series
Accession:
GSE8425
ID:
200008425
5.
Full record GDS2816

Ras-GRF1 deficiency effect on the hippocampus

Analysis of laser capture microdissected hippocampi of mutants lacking Ras-GRF1. Ras-GRF-1 is a guanine nucleotide exchange factor predominantly expressed in the central nervous system of mammals. Results provide insight into role of Ras-GRF1 in neural processes.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL339
Series:
GSE8425
6 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS2816
ID:
2816
6.

27_RA_RMA_Jan04_time_course

(Submitter supplied) This series represents murine dorsal neural tube bisected along the midline with one half from each embryo used for control and the other half treated with 10-6M RA dissolved in ethanol for 6, 12, 24 or 48 h. For 6 h exposures, the explants were cultured overnight on fibronectin coated 35mm dishes (Biocoat, Becton Dickinson Labware, Bedford, MA) in DMEM with 10% horse serum in order to allow for sufficient outgrowth of neural crest cells. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS773
Platform:
GPL81
27 Samples
Download data: CEL, EXP
Series
Accession:
GSE1588
ID:
200001588
7.
Full record GDS773

Retinoic acid teratogenic effect on cranial neural crest: time course

Expression profiling of cranial neural crest exposed to 1 uM retinoic acid (RA) at various lengths of time up to 48 hours. Neural crest obtained from 8.5 days postcoitum ICR embryos. Results provide insight into developmental pathways affected upon exposure to teratogenic concentrations of RA.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 agent, 4 time sets
Platform:
GPL81
Series:
GSE1588
27 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS773
ID:
773
8.

Expression data from brain tissue of Rattus norvegicus treated with D-Serine

(Submitter supplied) d-serine is naturally present throughout the human body. It is also used as add-on therapy for treatment-refractory schizophrenia. d-Serine interacts with the strychnine-insensitive glycine binding site of NMDA receptor, and this interaction could lead to potentially toxic activity (i.e., excitotoxicity) in brain tissue. The transcriptomic changes that occur in the brain after d-serine exposure have not been fully explored. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Dataset:
GDS3643
Platform:
GPL1355
24 Samples
Download data: CEL
Series
Accession:
GSE10748
ID:
200010748
9.
Full record GDS3643

D-serine effect on the brain: dose response

Analysis of forebrains of animals treated with up to 500 mg/kg D-serine for 96 hours. D-serine is involved in many physiological processes through its interaction with the glycine binding site of the NMDA receptor. Results provide insight into the impact of D-serine exposure on neuronal functions.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 agent, 6 dose sets
Platform:
GPL1355
Series:
GSE10748
24 Samples
Download data: CEL
DataSet
Accession:
GDS3643
ID:
3643
10.

whole brains from nicotinic acetylcholine receptor subunit mutant mice and littermate controls

(Submitter supplied) Studies using mice with beta4 nicotinic acetylcholine receptor (nAChR) subunit deficiency (beta4-/- mice) helped reveal the roles of this subunit in bradycardiac response to vagal stimulation, nicotine-induced seizure activity and anxiety. In order to identify genes that might be related to beta4-containing nAChRs activity, we compared the mRNA expression profiles of brains from beta4-/- and wild-type mice using Affymetrix U74Avr2 microarray. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS2309
Platform:
GPL81
11 Samples
Download data
Series
Accession:
GSE5320
ID:
200005320
11.
Full record GDS2309

Beta-4 nicotinic acetylcholine receptor subunit deficiency effect on the brain

Analysis of brains of beta-4 nicotinic acetylcholine receptor (nAChR) subunit null mutants. nAChRs are pentameric ion channels. Results provide insight into the molecular basis of the beta-4 subunit's role in the bradycardic response to vagal stimulation, nicotine-induced seizure, and anxiety.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL81
Series:
GSE5320
11 Samples
Download data
DataSet
Accession:
GDS2309
ID:
2309
12.

Selection of Neural Differentiation-Specific Genes by Comparing Profiles of Random Differentiation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS2227
Platform:
GPL2987
21 Samples
Download data
Series
Accession:
GSE5459
ID:
200005459
13.

Guided differentiation of mouse embryonic stem cell

(Submitter supplied) The mouse embryonic stem cell’s differentiation was guided by several treatments, and each stage of differentiation was examined. Keywords: development stage
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL2987
12 Samples
Download data
Series
Accession:
GSE3528
ID:
200003528
14.

Random differentiation of mouse embryonic stem cell

(Submitter supplied) Embryoid Bodies were dissociated and plated onto tissue culture dish in DMEM with fetal bovine serum and antibiotics for 4, 8, 12, 15, 21 day. Keywords: development stage
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL2987
12 Samples
Download data
Series
Accession:
GSE3527
ID:
200003527
15.
Full record GDS2227

Guided differentiation into dopaminergic neurons and random differentiation into embryoid bodies

Comparison of cells induced to differentiate into dopaminergic neurons by guided differentiation (GD) to those induced to differentiate into embryoid bodies (EBs) by random differentiation (RD). Cells at 3 stages of differentiation in the GD model and days 4 to 21 EBs in the RD model compared.
Organism:
Mus musculus
Type:
Expression profiling by array, log ratio, 7 development stage, 2 growth protocol sets
Platform:
GPL2987
Series:
GSE5459
21 Samples
Download data
DataSet
Accession:
GDS2227
ID:
2227
16.

Aortas of mice on high fat diet

(Submitter supplied) Expression profiles in aortas isolated from mouse strains C3H.2/HeJ and C57.2Bl/6. Mice were were either on a high fat diet or normal diet for 0, 4, 10, 24, or 40 weeks. Keywords: other
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS735
Platform:
GPL891
54 Samples
Download data
Series
Accession:
GSE1560
ID:
200001560
17.
Full record GDS735

High fat diet effect on aorta: time course

Comparison of gene expression in aortas of C57BL/6 and C3H/HeJ fed identical high fat diets at 0, 4, 8, 24, and 40 weeks. C57BL/6 has a greater tendency than C3H/HeJ to develop atherosclerotic aortic lesions when both fed identical high fat diets.
Organism:
Mus musculus
Type:
Expression profiling by array, log ratio, 2 growth protocol, 2 strain, 5 time sets
Platform:
GPL891
Series:
GSE1560
54 Samples
Download data
DataSet
Accession:
GDS735
ID:
735
18.

Inflammatory bladder response

(Submitter supplied) Bladders examined at 1, 4 and 24 hours after lipopolysaccharide, substance P or ovalbumin challenge. Keywords: other
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL144
12 Samples
Download data
Series
Accession:
GSE597
ID:
200000597
19.

Functional Gene Expression Differences between Inbred Alcohol-Preferring (iP) and non-preferring (iNP) Rats

(Submitter supplied) The objective of this study was to test the hypothesis that innate differences in gene expression in the brain could contribute to the differences in alcohol drinking or response to alcohol between adult male inbred alcohol-preferring (iP) and -non-preferring (iNP) rats. Gene expression was determined in the nucleus accumbens (ACB), amygdala (AMYG), frontal cortex (FC), caudate-putamen (CPU) and hippocampus (HIP) of alcohol-naïve adult male iP and iNP rats, using Affymetrix Rat Genome U34A microarrays (n = 6/strain). more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Dataset:
GDS2841
Platform:
GPL85
59 Samples
Download data: CEL
Series
Accession:
GSE4494
ID:
200004494
20.
Full record GDS2841

Alcohol-preferring inbred strain: brain

Analysis of various CNS regions of inbred alcohol-preferring and non-alcohol preferring animals that have not been exposed to alcohol. Results provide insight into the molecular basis of the difference in alcohol preference between the two strains.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 strain, 5 tissue sets
Platform:
GPL85
Series:
GSE4494
59 Samples
Download data: CEL
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