GEO DataSets

(Submitter supplied) An important, but rarely performed, test of Koch’s molecular postulates involves evaluating the capacity of candidate virulence genes to confer pathogenicity in otherwise non-virulent species. Unbiased genomic surveys of avirulent natural isolates might reveal rare variants possessing specific virulence features, which might prove useful in testing their functional sufficiency. Using a custom pan-genome array, we analyzed a panel of avirulent Burkholderia thailandensis (Bt) isolates related to Burkholderia pseudomallei (Bp), the causative agent of the often fatal human and animal disease melioidosis. more...

Organism:

Burkholderiales; Burkholderia thailandensis

Type:

Genome variation profiling by genome tiling array

Platform:

GPL9490

49 Samples

Download data: PAIR

(Submitter supplied) Using the NimbleGen proprietary photolithography Maskless Array Synthesizer (MAS) technology in situ oligo-synthesis, we fabricated a multi-species pan genome array that has 388943 probes, of which 366064 are data probes, 2074 control probes and 20,000 probes for backgroun estimation and correction. The make-up of these data probes are 55% (of which 60% from Bp K96243) for all sequenced Bp strains, 34% designed for all sequenced Bt strains (of which 90% from Bt E264) and finally 11% designed for Bc strain J2315. more...

Organism:

Burkholderiales

1 Series

49 Samples

Download data: NDF, POS