txid55429[Organism:noexp] - GEO DataSets

Select item 2001004381.

Therapeutic antibodies to ganglioside GD2 evolved from highly selective germline antibodies

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Rhodotorula; Bos taurus; Ovis aries; Ceratonia siliqua; Frangula alnus; Senegalia senegal; Dermestes lardarius; Quercus alba; Trypanosoma cruzi; Bothrops moojeni; Pachymenia carnosa; Gossypium hirsutum; Pandalus borealis; Oncorhynchus nerka; Homo sapiens; Sus scrofa domesticus; Gallus gallus; Oryctolagus cuniculus; Mus musculus; Human immunodeficiency virus 1; unidentified; Megathura crenulata

Type:: Protein profiling by protein array

Platforms:: GPL23565 GPL23566
55 Samples

Download data: GPR

Series

Accession:: GSE100438

ID:: 200100438

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001003102.

Therapeutic antibodies to ganglioside GD2 evolved from highly selective germline antibodies VII

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to evaluate the immunological evolution of antibodies to the glyco-antigen GD2. The goal is to determine germline and affinity mature antibody specificity and affinities/ Results: Affinity mature anti-GD2 antibodies 3F8 and ch14.18 had high affinity and were highly specific for the target GD2. Germline antibodies were also hihgly specific and had surprisingly high affinity. more...

Organism:: Trypanosoma cruzi; Gallus gallus; Pachymenia carnosa; Gossypium hirsutum; Rhodotorula; Homo sapiens; Bos taurus; Mus musculus; Human immunodeficiency virus 1; Ovis aries; Oryctolagus cuniculus; Megathura crenulata; Frangula alnus; Quercus alba; Pandalus borealis; Oncorhynchus nerka; Sus scrofa domesticus; Ceratonia siliqua; Bothrops moojeni; Senegalia senegal; Dermestes lardarius

Type:: Protein profiling by protein array

Platform:: GPL23566
7 Samples

Download data: GPR, TXT

Series

Accession:: GSE100310

ID:: 200100310

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001003093.

Therapeutic antibodies to ganglioside GD2 evolved from highly selective germline antibodies VI

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to evaluate the immunological evolution of antibodies to the glyco-antigen GD2. The goal is to determine germline and affinity mature antibody specificity and affinities/ Results: Affinity mature anti-GD2 antibodies 3F8 and ch14.18 had high affinity and were highly specific for the target GD2. Germline antibodies were also hihgly specific and had surprisingly high affinity. more...

Organism:: Quercus alba; Oryctolagus cuniculus; Megathura crenulata; Gossypium hirsutum; Rhodotorula; Homo sapiens; Bos taurus; Mus musculus; Human immunodeficiency virus 1; Trypanosoma cruzi; Gallus gallus; Bothrops moojeni; Pachymenia carnosa; Pandalus borealis; Oncorhynchus nerka; Sus scrofa domesticus; Ovis aries; Ceratonia siliqua; Frangula alnus; Senegalia senegal; Dermestes lardarius

Type:: Protein profiling by protein array

Platform:: GPL23566
7 Samples

Download data: GPR, TXT

Series

Accession:: GSE100309

ID:: 200100309

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001003084.

Therapeutic antibodies to ganglioside GD2 evolved from highly selective germline antibodies V

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to evaluate the immunological evolution of antibodies to the glyco-antigen GD2. The goal is to determine germline and affinity mature antibody specificity and affinities/ Results: Affinity mature anti-GD2 antibodies 3F8 and ch14.18 had high affinity and were highly specific for the target GD2. Germline antibodies were also hihgly specific and had surprisingly high affinity. more...

Organism:: Rhodotorula; Trypanosoma cruzi; Gallus gallus; Mus musculus; Human immunodeficiency virus 1; Bothrops moojeni; Pachymenia carnosa; Homo sapiens; Bos taurus; Quercus alba; Gossypium hirsutum; Oryctolagus cuniculus; Megathura crenulata; Pandalus borealis; Oncorhynchus nerka; Sus scrofa domesticus; Ovis aries; Ceratonia siliqua; Frangula alnus; Senegalia senegal; Dermestes lardarius

Type:: Protein profiling by protein array

Platform:: GPL23566
7 Samples

Download data: GPR, TXT

Series

Accession:: GSE100308

ID:: 200100308

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001003075.

Therapeutic antibodies to ganglioside GD2 evolved from highly selective germline antibodies IV

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to evaluate the immunological evolution of antibodies to the glyco-antigen GD2. The goal is to determine germline and affinity mature antibody specificity and affinities/ Results: Affinity mature anti-GD2 antibodies 3F8 and ch14.18 had high affinity and were highly specific for the target GD2. Germline antibodies were also hihgly specific and had surprisingly high affinity. more...

Organism:: Quercus alba; Gossypium hirsutum; Pandalus borealis; Oncorhynchus nerka; Homo sapiens; Trypanosoma cruzi; Bos taurus; Rhodotorula; Mus musculus; Human immunodeficiency virus 1; Bothrops moojeni; Senegalia senegal; Pachymenia carnosa; Dermestes lardarius; Gallus gallus; Sus scrofa domesticus; Ovis aries; Oryctolagus cuniculus; Ceratonia siliqua; Megathura crenulata; Frangula alnus

Type:: Protein profiling by protein array

Platform:: GPL23566
7 Samples

Download data: GPR, TXT

Series

Accession:: GSE100307

ID:: 200100307

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000998746.

Therapeutic antibodies to ganglioside GD2 evolved from highly selective germline antibodies III

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to evaluate the immunological evolution of antibodies to the glyco-antigen GD2. The goal is to determine germline and affinity mature antibody specificity and affinities/ Results: Affinity mature anti-GD2 antibodies 3F8 and ch14.18 had high affinity and were highly specific for the target GD2. Germline antibodies were also hihgly specific and had surprisingly high affinity. more...

Organism:: Trypanosoma cruzi; Gallus gallus; Mus musculus; Human immunodeficiency virus 1; Bothrops moojeni; Pachymenia carnosa; Gossypium hirsutum; Rhodotorula; Homo sapiens; Bos taurus; Quercus alba; Oryctolagus cuniculus; Megathura crenulata; Pandalus borealis; Oncorhynchus nerka; Sus scrofa domesticus; Ovis aries; Ceratonia siliqua; Frangula alnus; Senegalia senegal; Dermestes lardarius

Type:: Protein profiling by protein array

Platform:: GPL23566
7 Samples

Download data: GPR, TXT

Series

Accession:: GSE99874

ID:: 200099874

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000998737.

Therapeutic antibodies to ganglioside GD2 evolved from highly selective germline antibodies II

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to evaluate the immunological evolution of antibodies to the glyco-antigen GD2. The goal is to determine germline and affinity mature antibody specificity and affinities/ Results: Affinity mature anti-GD2 antibodies 3F8 and ch14.18 had high affinity and were highly specific for the target GD2. Germline antibodies were also hihgly specific and had surprisingly high affinity. more...

Organism:: Quercus alba; Gossypium hirsutum; Oncorhynchus nerka; Homo sapiens; Bos taurus; Rhodotorula; Trypanosoma cruzi; Mus musculus; Human immunodeficiency virus 1; Bothrops moojeni; Senegalia senegal; Pachymenia carnosa; Pandalus borealis; Gallus gallus; Sus scrofa domesticus; Ovis aries; Oryctolagus cuniculus; Ceratonia siliqua; Megathura crenulata; Frangula alnus; Dermestes lardarius

Type:: Protein profiling by protein array

Platform:: GPL23566
14 Samples

Download data: GPR, TXT

Series

Accession:: GSE99873

ID:: 200099873

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000998728.

Therapeutic antibodies to ganglioside GD2 evolved from highly selective germline antibodies I

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to evaluate the immunological evolution of antibodies to the glyco-antigen GD2. The goal is to determine germline and affinity mature antibody specificity and affinities/ Results: Affinity mature anti-GD2 antibodies 3F8 and ch14.18 had high affinity and were highly specific for the target GD2. Germline antibodies were also hihgly specific and had surprisingly high affinity. more...

Organism:: Rhodotorula; Bos taurus; Mus musculus; Human immunodeficiency virus 1; Ceratonia siliqua; Bothrops moojeni; Senegalia senegal; Pachymenia carnosa; Dermestes lardarius; Trypanosoma cruzi; Quercus alba; Gossypium hirsutum; Pandalus borealis; Oncorhynchus nerka; Homo sapiens; Sus scrofa domesticus; Gallus gallus; Ovis aries; Oryctolagus cuniculus; unidentified; Megathura crenulata; Frangula alnus

Type:: Protein profiling by protein array

Platform:: GPL23565
6 Samples

Download data: GPR, TXT

Series

Accession:: GSE99872

ID:: 200099872

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000830879.

Whole-Cell Cancer Vaccines Induce Large Antibody Responses to Carbohydrates and Glycoproteins

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to profile anti-glycan immune responses to whole-cell vaccines: GVAX Pancreas, K562-GM and H1299. The aim was to indentify anti-glycan antibody responses relevent to patient clinical outcomes Results: Immune responses to non-human antigens bovine fetuin and alpha-Gal antigens were identified induced by GVAX Pancreas. The magnitude of these responses inversely correlate with patient survival. more...

Organism:: Trypanosoma cruzi; Gallus gallus; Bothrops moojeni; Pachymenia carnosa; Pandalus borealis; Oncorhynchus nerka; Ovis aries; Ceratonia siliqua; Frangula alnus; Senegalia senegal; Dermestes lardarius; Quercus alba; Oryctolagus cuniculus; Megathura crenulata; Gossypium hirsutum; Homo sapiens; Bos taurus; Mus musculus; Human immunodeficiency virus 1

Type:: Other

Platform:: GPL21991
168 Samples

Download data: GPR, TXT

Series

Accession:: GSE83087

ID:: 200083087

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20006840510.

A Simple, Inexpensive Strategy for Predicting Potential Beneficial Clinical Responses on Prostate Cancer Vaccine Therapy

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Gossypium hirsutum; Rhodotorula; Homo sapiens; Bos taurus; Mus musculus; Quercus alba; Megathura crenulata; Pandalus borealis; Oncorhynchus nerka; Ovis aries; Ceratonia siliqua; Frangula alnus; Senegalia senegal; Dermestes lardarius; Trypanosoma cruzi; Gallus gallus; Bothrops moojeni; Pachymenia carnosa

Type:: Other

Platforms:: GPL20116 GPL20117
331 Samples

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Series

Accession:: GSE68405

ID:: 200068405

PubMed Full text in PMC Similar studies

Select item 20006840311.

Development of a glycan microarray based method for ABO blood typing

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to develop a novel method to assign ABO blood type. The method will then be applied to samples from patients treated with PROSTVAC to determine if blood type correlates with survival Results: Many blood group A and B antigens correlate with blood type. Blood typing is best achieved using a combination of 10 signals Conclusion: ABO blood type can be determined with greater than 97% accuracy using only 4 microliters of serum.

Organism:: Trypanosoma cruzi; Bos taurus; Quercus alba; Gossypium hirsutum; Pandalus borealis; Oncorhynchus nerka; Homo sapiens; Gallus gallus; Ovis aries; Ceratonia siliqua; Megathura crenulata; Frangula alnus; Rhodotorula; Mus musculus; Bothrops moojeni; Senegalia senegal; Pachymenia carnosa; Dermestes lardarius

Type:: Other

Platform:: GPL20116
220 Samples

Download data: TXT

Series

Accession:: GSE68403

ID:: 200068403

PubMed Full text in PMC Similar studies

Select item 20005041012.

Anti-glycan humoral responses after vaccination with PROSTVAC-VF

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Medicago sativa; Gallus gallus; Megathura crenulata; Gossypium hirsutum; Pandalus borealis; Homo sapiens; Quercus alba; Bothrops moojeni; Pachymenia carnosa; Rhodotorula; Bos taurus; Ovis aries; Mus musculus; Frangula alnus; Senegalia senegal; Dermestes lardarius

Type:: Protein profiling by protein array

Platforms:: GPL16242 GPL16262
564 Samples

Download data: TXT

Series

Accession:: GSE50410

ID:: 200050410

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Select item 20005023913.

Post-vaccination serum anti-glycan total Ig antibodies of 113 subjects in a clinical trial of PROSTVAC-VF, a therapeutic cancer vaccine. (Dilution = 1:200)

(Submitter supplied) Purpose: There is evidence that therapeutic cancer vaccines can lengthen survival for some cancer patients, but responses vary widely from one person to another. Methods to predict clinical outcomes will advance the field and provide new insights into critical determinants of in vivo efficacy. This study uses a high-throughput glycan microarray to assess correlations between a subject's overall survival after receiving PROSTVAC-VF and his anti-glycan humoral responses occuring in the first months after treatment with PROSTVAC-VF. more...

Organism:: Gossypium hirsutum; Rhodotorula; Homo sapiens; Bos taurus; Mus musculus; Quercus alba; Ovis aries; Megathura crenulata; Pandalus borealis; Frangula alnus; Senegalia senegal; Dermestes lardarius; Medicago sativa; Gallus gallus; Bothrops moojeni; Pachymenia carnosa

Type:: Protein profiling by protein array

Platform:: GPL16242
113 Samples

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Series

Accession:: GSE50239

ID:: 200050239

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Select item 20005023714.

Baseline serum anti-glycan IgM antibodies of 113 subjects in a clinical trial of PROSTVAC-VF, a therapeutic cancer vaccine. (Dilution = 1:50)

(Submitter supplied) Purpose: There is evidence that therapeutic cancer vaccines can lengthen survival for some cancer patients, but responses vary widely from one person to another. Methods to predict clinical outcomes will advance the field and provide new insights into critical determinants of in vivo efficacy. This study uses a high-throughput glycan microarray to assess correlations between a subject's overall survival after receiving PROSTVAC-VF and his anti-glycan humoral responses occuring in the first months after treatment with PROSTVAC-VF. more...

Organism:: Homo sapiens; Bos taurus; Quercus alba; Gossypium hirsutum; Medicago sativa; Pandalus borealis; Gallus gallus; Ovis aries; Megathura crenulata; Frangula alnus; Dermestes lardarius; Rhodotorula; Mus musculus; Bothrops moojeni; Senegalia senegal; Pachymenia carnosa

Type:: Protein profiling by protein array

Platform:: GPL16242
113 Samples

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Series

Accession:: GSE50237

ID:: 200050237

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Select item 20005023615.

Baseline serum anti-glycan total Ig antibodies of 113 subjects in a clinical trial of PROSTVAC-VF, a therapeutic cancer vaccine. (Dilution = 1:50)

(Submitter supplied) Purpose: There is evidence that therapeutic cancer vaccines can lengthen survival for some cancer patients, but responses vary widely from one person to another. Methods to predict clinical outcomes will advance the field and provide new insights into critical determinants of in vivo efficacy. This study uses a high-throughput glycan microarray to assess correlations between a subject's overall survival after receiving PROSTVAC-VF and his anti-glycan humoral responses occuring in the first months after treatment with PROSTVAC-VF. more...

Organism:: Rhodotorula; Bos taurus; Mus musculus; Bothrops moojeni; Senegalia senegal; Pachymenia carnosa; Dermestes lardarius; Medicago sativa; Gallus gallus; Ovis aries; Megathura crenulata; Frangula alnus; Quercus alba; Gossypium hirsutum; Pandalus borealis; Homo sapiens

Type:: Protein profiling by protein array

Platform:: GPL16242
113 Samples

Download data

Series

Accession:: GSE50236

ID:: 200050236

Analyze with GEO2R

Select item 20005023516.

Post-vaccination serum anti-glycan IgG antibodies of 113 subjects in a clinical trial of PROSTVAC-VF, a therapeutic cancer vaccine. (Dilution = 1:50)

(Submitter supplied) Purpose: There is evidence that therapeutic cancer vaccines can lengthen survival for some cancer patients, but responses vary widely from one person to another. Methods to predict clinical outcomes will advance the field and provide new insights into critical determinants of in vivo efficacy. This study uses a high-throughput glycan microarray to assess correlations between a subject's overall survival after receiving PROSTVAC-VF and his anti-glycan humoral responses occuring in the first months after treatment with PROSTVAC-VF. more...

Organism:: Quercus alba; Bothrops moojeni; Pachymenia carnosa; Gossypium hirsutum; Pandalus borealis; Homo sapiens; Medicago sativa; Gallus gallus; Ovis aries; Megathura crenulata; Frangula alnus; Rhodotorula; Bos taurus; Mus musculus; Senegalia senegal; Dermestes lardarius

Type:: Protein profiling by protein array

Platform:: GPL16242
113 Samples

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Series

Accession:: GSE50235

ID:: 200050235

Analyze with GEO2R

Select item 20005023317.

Post-vaccination serum anti-glycan total Ig antibodies of 28 subjects in a clinical trial of PROSTVAC-VF, a therapeutic cancer vaccine. (Dilution = 1:200)

(Submitter supplied) Purpose: There is evidence that therapeutic cancer vaccines can lengthen survival for some cancer patients, but responses vary widely from one person to another. Methods to predict clinical outcomes will advance the field and provide new insights into critical determinants of in vivo efficacy. This study uses a high-throughput glycan microarray to assess correlations between a subject's overall survival after receiving PROSTVAC-VF and his anti-glycan humoral responses occuring in the first months after treatment with PROSTVAC-VF. more...

Organism:: Quercus alba; Bothrops moojeni; Pachymenia carnosa; Pandalus borealis; Gallus gallus; Homo sapiens; Gossypium hirsutum; Rhodotorula; Mus musculus; Bos taurus; Ovis aries; Megathura crenulata; Frangula alnus; Senegalia senegal; Dermestes lardarius

Type:: Protein profiling by protein array

Platform:: GPL16262
28 Samples

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Series

Accession:: GSE50233

ID:: 200050233

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Select item 20005023218.

Post-vaccination serum anti-glycan total Ig antibodies of 28 subjects in a clinical trial of PROSTVAC-VF, a therapeutic cancer vaccine. (Dilution = 1:50)

(Submitter supplied) Purpose: There is evidence that therapeutic cancer vaccines can lengthen survival for some cancer patients, but responses vary widely from one person to another. Methods to predict clinical outcomes will advance the field and provide new insights into critical determinants of in vivo efficacy. This study uses a high-throughput glycan microarray to assess correlations between a subject's overall survival after receiving PROSTVAC-VF and his anti-glycan humoral responses occuring in the first months after treatment with PROSTVAC-VF. more...

Organism:: Quercus alba; Pandalus borealis; Bothrops moojeni; Senegalia senegal; Pachymenia carnosa; Dermestes lardarius; Ovis aries; Megathura crenulata; Frangula alnus; Gossypium hirsutum; Rhodotorula; Homo sapiens; Bos taurus; Mus musculus; Gallus gallus

Type:: Protein profiling by protein array

Platform:: GPL16262
28 Samples

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Series

Accession:: GSE50232

ID:: 200050232

Analyze with GEO2R

Select item 20005023119.

Post-vaccination serum anti-glycan IgM antibodies of 28 subjects in a clinical trial of PROSTVAC-VF, a therapeutic cancer vaccine. (Dilution = 1:50)

(Submitter supplied) Purpose: There is evidence that therapeutic cancer vaccines can lengthen survival for some cancer patients, but responses vary widely from one person to another. Methods to predict clinical outcomes will advance the field and provide new insights into critical determinants of in vivo efficacy. This study uses a high-throughput glycan microarray to assess correlations between a subject's overall survival after receiving PROSTVAC-VF and his anti-glycan humoral responses occuring in the first months after treatment with PROSTVAC-VF. more...

Organism:: Quercus alba; Pandalus borealis; Bothrops moojeni; Senegalia senegal; Dermestes lardarius; Gallus gallus; Pachymenia carnosa; Gossypium hirsutum; Rhodotorula; Homo sapiens; Bos taurus; Mus musculus; Ovis aries; Megathura crenulata; Frangula alnus

Type:: Protein profiling by protein array

Platform:: GPL16262
28 Samples

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Series

Accession:: GSE50231

ID:: 200050231

Analyze with GEO2R

Select item 20005023020.

Post-vaccination serum anti-glycan IgG antibodies of 28 subjects in a clinical trial of PROSTVAC-VF, a therapeutic cancer vaccine. (Dilution = 1:50)

(Submitter supplied) Purpose: There is evidence that therapeutic cancer vaccines can lengthen survival for some cancer patients, but responses vary widely from one person to another. Methods to predict clinical outcomes will advance the field and provide new insights into critical determinants of in vivo efficacy. This study uses a high-throughput glycan microarray to assess correlations between a subject's overall survival after receiving PROSTVAC-VF and his anti-glycan humoral responses occuring in the first months after treatment with PROSTVAC-VF. more...

Organism:: Pandalus borealis; Ovis aries; Frangula alnus; Senegalia senegal; Dermestes lardarius; Quercus alba; Megathura crenulata; Gossypium hirsutum; Rhodotorula; Homo sapiens; Bos taurus; Mus musculus; Gallus gallus; Bothrops moojeni; Pachymenia carnosa

Type:: Protein profiling by protein array

Platform:: GPL16262
28 Samples

Download data

Series

Accession:: GSE50230

ID:: 200050230

Analyze with GEO2R

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