GEO DataSets

(Submitter supplied) MicroRNAs profile of circulating CD4+ T Cells in Aged Patients with Atherosclerosis Obliterans comparing healthy persons without symptoms or lesion associated with atherosclerosis.

Organism:

Human alphaherpesvirus 2; Lymphocryptovirus; Homo sapiens; Rhadinovirus; Human immunodeficiency virus 1; Merkel cell polyomavirus; JC polyomavirus

Type:

Non-coding RNA profiling by array

Platform:

GPL26002

14 Samples

Download data: GPR, XLSX

(Submitter supplied) The potential mechanism were successfully illustrated through detecting different expression of microRNAs in between proinflammatory high density lipprotein (pHDL), nomal high density lipprotein (nHDL) and control group, to study whether microRNAs play important roles in the endothelial dysfunction caused by pHDL.

Organism:

Homo sapiens; Rhadinovirus; JC polyomavirus; Human alphaherpesvirus 2; Lymphocryptovirus; Merkel cell polyomavirus; Human immunodeficiency virus 1

Type:

Non-coding RNA profiling by array

Platform:

GPL29064

3 Samples

Download data: XLS

(Submitter supplied) The expression profile of miRNAs in soft palate muscle of patients with OSAHS (obstructive sleep apnea/hypopnea syndrome) and chronic tonsillitis was examined using miRNA microarray analysis. Combining with the following real time PCR and bioinformatics analysis, the physiological importance of the miRNA-autophagy interconnection is far more likely to be elucidated.

Organism:

Human alphaherpesvirus 2; JC polyomavirus; Betapolyomavirus hominis; Human alphaherpesvirus 1; Cytomegalovirus; Lymphocryptovirus; Betapolyomavirus macacae; Homo sapiens; Rhadinovirus; Human immunodeficiency virus 1; Merkel cell polyomavirus

Type:

Non-coding RNA profiling by array

Platform:

GPL19128

8 Samples

Download data: GPR, TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens; Rhadinovirus; Merkel cell polyomavirus; Human alphaherpesvirus 1; Cytomegalovirus; Lymphocryptovirus; Betapolyomavirus macacae; Human alphaherpesvirus 2; JC polyomavirus; Betapolyomavirus hominis; Human immunodeficiency virus 1

Type:

Expression profiling by array; Expression profiling by high throughput sequencing; Non-coding RNA profiling by array; Non-coding RNA profiling by high throughput sequencing

Platforms:

GPL18573 GPL571 GPL19128

75 Samples

Download data: CEL, TXT

(Submitter supplied) CDK4/6 inhibition is now part of the standard armamentarium for patients with estrogen receptor (ER)-positive breast cancer, so that defining mechanisms of resistance is a pressing issue. Here, we identify increased CDK6 expression as a key determinant of acquired resistance after exposure to palbociclib in ER-positive breast cancer cells. Increased CDK6 in resistant cells was dependent on TGF-β pathway suppression via miR-432-5p expression. more...

Organism:

Cytomegalovirus; Betapolyomavirus macacae; JC polyomavirus; Human immunodeficiency virus 1; Merkel cell polyomavirus; Human alphaherpesvirus 2; Lymphocryptovirus; Homo sapiens; Human alphaherpesvirus 1; Rhadinovirus; Betapolyomavirus hominis

Type:

Non-coding RNA profiling by array

Platform:

GPL19128

9 Samples

Download data: TXT

(Submitter supplied) microRNAs profiling of human serum comparing control fertile women with women who had experienced repeated implantation failure after ovarian stimulation and IVF-ET. Repeated implantation failure was defined as women who had undergone≥3 failed cycles with high-grade embryos were transferred.

Organism:

Human alphaherpesvirus 2; Lymphocryptovirus; Betapolyomavirus hominis; Human alphaherpesvirus 1; Cytomegalovirus; Betapolyomavirus macacae; Homo sapiens; Rhadinovirus; Merkel cell polyomavirus; JC polyomavirus; Human immunodeficiency virus 1

Type:

Non-coding RNA profiling by array

Platform:

GPL19128

6 Samples

Download data: GPR, TXT

(Submitter supplied) We first examined changes of miRNAs and expression using microarrays ( Exiqon miRCURY™ microarray LNA v.18.0) of GCs from 10 bPOI and 10 age and BMI matched normal control women. Seventy-five miRNAs (Fold Change [FC]>2, P<0.05) were identified differentially expressed between bPOI patients and control women.

Organism:

Human alphaherpesvirus 1; Human alphaherpesvirus 2; Lymphocryptovirus; JC polyomavirus; Human immunodeficiency virus 1; Merkel cell polyomavirus; Cytomegalovirus; Betapolyomavirus macacae; Homo sapiens; Rhadinovirus; Betapolyomavirus hominis

Type:

Non-coding RNA profiling by array

Platform:

GPL19128

20 Samples

Download data: GPR, TXT

(Submitter supplied) The aim of this study was to determine differences in microRNA expression profiles of gastric cancer and adjacent healthy gastric mucosa. Both types of tissue samples were collected during operative procedures of 20 patients. microRNA expression was determined by miRNA microarrays.

Organism:

Homo sapiens; Rhadinovirus; Human immunodeficiency virus 1; Merkel cell polyomavirus; JC polyomavirus; Betapolyomavirus hominis; Human alphaherpesvirus 1; Human alphaherpesvirus 2; Cytomegalovirus; Lymphocryptovirus; Betapolyomavirus macacae

Type:

Non-coding RNA profiling by array

Platform:

GPL19071

40 Samples

Download data: TXT

(Submitter supplied) Exosomal and cellular miRNA expression levels were measured using a microRNA chip array or quantitative reverse transcription PCR (qRT-PCR). miR-24-3p was enriched in T-EXOs from the sera of NPC patients and NPC cells, which was correlated with worse disease-free survival (DFS). Exosomes (miR-24-3p-sponge-EXO) released from miR-24-3p-sponge-TW03 cells failed to inhibit T-cell proliferation and Th1 and Th17 differentiation or to induce Treg differentiation in vitro, compared with controlNC -sponge-EXO. more...

Organism:

Rattus norvegicus; JC polyomavirus; Murid gammaherpesvirus 4; Betapolyomavirus hominis; Human alphaherpesvirus 1; Human alphaherpesvirus 2; Cytomegalovirus; Lymphocryptovirus; Betapolyomavirus macacae; Homo sapiens; Human betaherpesvirus 5; Rhadinovirus; Human immunodeficiency virus 1; Merkel cell polyomavirus; Mus musculus

Type:

Non-coding RNA profiling by array

Platform:

GPL16016

2 Samples

Download data: GPR

(Submitter supplied) This study was designed to investigate the miRNA expression profilein human chorionic villi from early recurrent miscarriage. We identified 155 miRNAs exhibiting over 2-fold change in expression levels (P<0.05) by microarray,

Organism:

Homo sapiens; Rhadinovirus; Merkel cell polyomavirus; Human immunodeficiency virus 1; Human alphaherpesvirus 2; Lymphocryptovirus; JC polyomavirus; Betapolyomavirus hominis; Human alphaherpesvirus 1; Cytomegalovirus; Betapolyomavirus macacae

Type:

Non-coding RNA profiling by array

Platform:

GPL20917

10 Samples

Download data: TXT

(Submitter supplied) This is a miRNA expression analysis by microarray. Comparison was made beween Ulcerative Colitis (UC) vs control, Active UC vs Remission, Ascending Colon vs Rectosigmoid area of Colon. The samples were labeled using the miRCURY LNA™ microRNA Hi-Power Labeling Kit, Hy3™/Hy5™ and hybridized on the miRCURY LNA™ microRNA Array (7th gen) following the scheme you outlined in the sample submission form. The technical data quality assessment showed that the labeling was successful as all capture probes for the control spike-in oligo nucleotides produced signals in the expected range. more...

Organism:

JC polyomavirus; Human immunodeficiency virus 1; Human alphaherpesvirus 2; Lymphocryptovirus; Betapolyomavirus hominis; Rhadinovirus; Merkel cell polyomavirus; Homo sapiens; Human alphaherpesvirus 1; Cytomegalovirus; Betapolyomavirus macacae

Type:

Non-coding RNA profiling by array

Platform:

GPL19128

6 Samples

Download data: CSV, TXT, XLSX

(Submitter supplied) miRNA profiling of S. japonicum infected mouse plasma comparing control untreated mouse plasma. Schistosomiasis, caused by dioecious flatworms in the genus Schistosoma, is torturing people predominantly in the developing countries. Knowledge on schistosome-host interaction and its parasitism may result in the development of novel strategies for schistosomiasis control. MicroRNAs (miRNAs) are involved in a wide range of biological processes including development, cell proliferation, metabolism ,signal transduction, et al. more...

Organism:

Homo sapiens; Rhadinovirus; Murid gammaherpesvirus 4; Betapolyomavirus hominis; Mus musculus; Human alphaherpesvirus 1; Human betaherpesvirus 5; Human immunodeficiency virus 1; Cytomegalovirus; JC polyomavirus; Betapolyomavirus macacae; Rattus norvegicus; Human alphaherpesvirus 2; Lymphocryptovirus; Merkel cell polyomavirus

Type:

Non-coding RNA profiling by array

Platform:

GPL16016

4 Samples

Download data: GAL, GPR, TXT, XLS

(Submitter supplied) Psychological stress is highly prevalent in modern society. Both epidemiologic and experimental animal studies demonstrate that chronic psychological stress exerts adverse effects on the initiation and/or progression of many diseases. Here, using a mouse model of restraint stress, we report the discovery of a novel signaling pathway linking paternal stress exposure to the reprogram of hepatic gluconeogenesis in the offspring. more...

Organism:

Mus musculus; Human alphaherpesvirus 1; Human immunodeficiency virus 1; Human alphaherpesvirus 2; Lymphocryptovirus; Merkel cell polyomavirus; Cytomegalovirus; JC polyomavirus; Betapolyomavirus macacae; Homo sapiens; Rhadinovirus; Betapolyomavirus hominis

Type:

Non-coding RNA profiling by array

Platform:

GPL19128

6 Samples

Download data: GPR, TXT

(Submitter supplied) miRNA profiles of the Young-MSC-MVs and Old-MSC-MVs were analyzed with a quantitative PCR (qPCR)-based array of the whole rat genome. Further analysis revealed the expression of miR-344a, miR-133b-3p, miR-294, miR-423-3p, and miR-872-3p was significantly downregulated in Old-MSC-MVs than in Young-MSC-MVs (p<0.05).

Organism:

Rattus norvegicus; Human alphaherpesvirus 2; JC polyomavirus; Betapolyomavirus hominis; Human immunodeficiency virus 1; Homo sapiens; Rhadinovirus; Merkel cell polyomavirus; Human alphaherpesvirus 1; Cytomegalovirus; Lymphocryptovirus; Betapolyomavirus macacae

Type:

Non-coding RNA profiling by array

Platform:

GPL19128

6 Samples

Download data: GPR, TXT

(Submitter supplied) In order to determine the serum microRNAs profile from middle-old aged patients with acute ischemic stroke and investigate possible diagnostic value of these differential microRNAs.The blood samples of 117 IS patients and 82 healthy people were collected. Differential miRNAs in serum from IS and control were screened with miRNA microarray analysis, and the expression of selected miRNAs were validated by quantitative reverse-transcriptase polymerase chain reaction assays (qRT-PCR). more...

Organism:

Human alphaherpesvirus 2; Lymphocryptovirus; Merkel cell polyomavirus; Cytomegalovirus; JC polyomavirus; Betapolyomavirus macacae; Human alphaherpesvirus 1; Human immunodeficiency virus 1; Homo sapiens; Rhadinovirus; Betapolyomavirus hominis

Type:

Non-coding RNA profiling by array

Platform:

GPL19071

5 Samples

Download data: GPR

(Submitter supplied) This study aimed to investigate the molecular mechanism responsible for primary open-angle glaucoma (POAG) progression. We analyzed microRNAs (miRNAs) expression profiling in aqueous humor (AH) of both POAG patients and normal controls, using a microarray-based approach. Subsequently, differentially expressed miRNAs (DEmiRNAs) were identified using Bayes moderated t-test. Next, DEmiRNAs target genes were predicted based on miRNA databases, followed by GO analysis and pathway analysis using DAVID. more...

Organism:

Homo sapiens; Rhadinovirus; Human immunodeficiency virus 1; Merkel cell polyomavirus; JC polyomavirus; Betapolyomavirus hominis; Human alphaherpesvirus 1; Human alphaherpesvirus 2; Cytomegalovirus; Lymphocryptovirus; Betapolyomavirus macacae

Type:

Non-coding RNA profiling by array

Platform:

GPL19128

6 Samples

Download data: GPR, TXT

(Submitter supplied) Recent studies show that mantle cell lymphoma (MCL) express aberrant miRNA profiles, however, the clinical effect of miRNA expression has not previously been examined and validated in prospective, large, homogenously treated cohorts. We analyzed diagnostic MCL samples from the Nordic MCL2 and MCL3 clinical trials, in which all patients had received Rituximab-high-dose cytarabin alternating with Rituximab-maxiCHOP, followed by BEAM and autologous stem cell support. more...

Organism:

Human alphaherpesvirus 1; Human alphaherpesvirus 2; Cytomegalovirus; Lymphocryptovirus; Betapolyomavirus macacae; JC polyomavirus; Betapolyomavirus hominis; Homo sapiens; Rhadinovirus; Human immunodeficiency virus 1; Merkel cell polyomavirus

Type:

Non-coding RNA profiling by array

Platform:

GPL19128

76 Samples

Download data: GPR, TXT

(Submitter supplied) Recent evidence supports a role of microRNAs in cancer and psychiatric disorders such as schizophrenia and bipolar disorder, through their regulatory role on the expression of multiple genes. The rather rare co-morbidity of cancer and schizophrenia is an old hypothesis which needs further research on microRNAs as molecules that might exert their oncosuppressive or oncogenic activity in the context of their role in psychiatric disorders The expression pattern of a variety of different microRNAs was investigated in patients (N=6) suffering from schizophrenia termed control, patients with a solid tumor (N=10) and patients with both schizophrenia and tumor (N=8). more...

Organism:

Homo sapiens; Human alphaherpesvirus 1; Human betaherpesvirus 5; human gammaherpesvirus 4; Human alphaherpesvirus 2; Lymphocryptovirus; Human betaherpesvirus 6B; Betapolyomavirus hominis; Rhadinovirus; Betapolyomavirus macacae; Macacine alphaherpesvirus 1; Herpesvirus saimiri (strain 11); JC polyomavirus; Human immunodeficiency virus 1; Human gammaherpesvirus 8; Merkel cell polyomavirus

Type:

Non-coding RNA profiling by array

Platforms:

GPL19677 GPL19676

24 Samples

Download data: TXT, XLS

(Submitter supplied) To identify tumor compartment-specific microRNA expression in stage I non-small cell lung cancer in humans, surgically resected and formalin-fixed tumor tissues were used in laser capture microdissection to isolate tumor epithelia and stroma. Total RNA extracted from the microdissectates was analyzed for microRNA expression using the 7th generation miRCURY™ locked nucleic acid microarray platform (Exiqon®, Vedbaek, Denmark).

Organism:

Rattus norvegicus; JC polyomavirus; Murid gammaherpesvirus 4; Betapolyomavirus hominis; Mus musculus; Homo sapiens; Human betaherpesvirus 5; Rhadinovirus; Human immunodeficiency virus 1; Merkel cell polyomavirus; Human alphaherpesvirus 1; Human alphaherpesvirus 2; Cytomegalovirus; Lymphocryptovirus; Betapolyomavirus macacae

Type:

Non-coding RNA profiling by array

Platform:

GPL16294

136 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens; Human alphaherpesvirus 1; Human betaherpesvirus 5; Rhadinovirus; Human immunodeficiency virus 1; Merkel cell polyomavirus; Murid gammaherpesvirus 4; JC polyomavirus; Betapolyomavirus hominis; Human alphaherpesvirus 2; Cytomegalovirus; Lymphocryptovirus; Betapolyomavirus macacae

Type:

Expression profiling by array; Non-coding RNA profiling by array

Platforms:

GPL6244 GPL16287

112 Samples

Download data: CEL, TXT