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Items: 6

1.

Dynamic shifts in occupancy by TAL1 are guided by GATA factors and drive large-scale reprogramming of gene expression during hematopoiesis

(Submitter supplied) We used mouse ENCODE data along with complementary data from other laboratories to study the dynamics of occupancy and the role in gene regulation of the transcription factor TAL1, a critical regulator of hematopoiesis, at multiple stages of hematopoietic differentiation. We combined ChIP-seq and RNA-seq data in six mouse cell types representing a progression from multilineage precursors to differentiated erythroblasts and megakaryocytes. more...
Organism:
Mus musculus
Type:
Other
4 related Platforms
81 Samples
Download data: BEDGRAPH, BIGWIG, BROADPEAK, TXT, WIG
Series
Accession:
GSE51338
ID:
200051338
2.

Divergent functions of hematopoietic transcription factors in lineage priming and differentiation during erythro-megakaryopoiesis

(Submitter supplied) Combinatorial actions of relatively few transcription factors control hematopoietic differentiation. To investigate this process in erythro-megakaryopoiesis, we correlated the genome-wide chromatin occupancy signatures of four master hematopoietic transcription factors (GATA1, GATA2, TAL1, and FLI1) and three diagnostic histone modification marks with the gene expression changes that occur during development of primary cultured megakaryocytes (MEG) and primary erythroblasts (ERY) from murine fetal liver hematopoietic stem/progenitor cells. more...
Organism:
Mus musculus
Type:
Other
Platforms:
GPL13112 GPL9250 GPL6246
42 Samples
Download data: BEDGRAPH, BIGWIG, BROADPEAK, CEL, TXT
Series
Accession:
GSE51337
ID:
200051337
3.

A comparative encyclopedia of DNA elements in the mouse genome

(Submitter supplied) The laboratory mouse shares the majority of its protein-coding genes with humans, making it the premier model organism in biomedical research, yet the two mammals differ in significant ways. To gain greater insights into both shared and species-specific transcriptional and cellular regulatory programs in the mouse, the Mouse ENCODE Consortium has mapped transcription, DNase I hypersensitivity, transcription factor binding, chromatin modifications and replication domains throughout the mouse genome in diverse cell and tissue types. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome variation profiling by genome tiling array; Genome binding/occupancy profiling by high throughput sequencing
8 related Platforms
588 Samples
Download data: BAM, BEDRNAELEMENTS, BIGWIG, BROADPEAK, NARROWPEAK, PAIR
Series
Accession:
GSE49847
ID:
200049847
4.

Transcription Factor Binding Sites by ChIP-seq from ENCODE/PSU

(Submitter supplied) This data was generated by ENCODE. If you have questions about the data, contact the submitting laboratory directly (Ross Hardison mailto:rch8@psu.edu). If you have questions about the Genome Browser track associated with this data, contact ENCODE (mailto:genome@soe.ucsc.edu). Rationale for the Mouse ENCODE project Our knowledge of the function of genomic DNA sequences comes from three basic approaches. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL13112 GPL9250
38 Samples
Download data: BIGWIG, BROADPEAK, TXT
Series
Accession:
GSE36029
ID:
200036029
5.

Illumina HiSeq 2000 (Mus musculus)

Platform
Accession:
GPL13112
ID:
100013112
6.

PSU_ChipSeq_Megakaryo_TAL1_(SC-12984)

Organism:
Mus musculus
Source name:
Megakaryo
Platform:
GPL13112
Series:
GSE36029 GSE49847 GSE51337 GSE51338
Download data: BIGWIG, BROADPEAK
Sample
Accession:
GSM995447
ID:
300995447
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