GSM995447[Accession] - GEO DataSets

Select item 2000513381.

Dynamic shifts in occupancy by TAL1 are guided by GATA factors and drive large-scale reprogramming of gene expression during hematopoiesis

(Submitter supplied) We used mouse ENCODE data along with complementary data from other laboratories to study the dynamics of occupancy and the role in gene regulation of the transcription factor TAL1, a critical regulator of hematopoiesis, at multiple stages of hematopoietic differentiation. We combined ChIP-seq and RNA-seq data in six mouse cell types representing a progression from multilineage precursors to differentiated erythroblasts and megakaryocytes. more...

Organism:: Mus musculus

Type:: Other

4 related Platforms
81 Samples

Download data: BEDGRAPH, BIGWIG, BROADPEAK, TXT, WIG

Series

Accession:: GSE51338

ID:: 200051338

PubMed Full text in PMC Similar studies

Select item 2000513372.

Divergent functions of hematopoietic transcription factors in lineage priming and differentiation during erythro-megakaryopoiesis

(Submitter supplied) Combinatorial actions of relatively few transcription factors control hematopoietic differentiation. To investigate this process in erythro-megakaryopoiesis, we correlated the genome-wide chromatin occupancy signatures of four master hematopoietic transcription factors (GATA1, GATA2, TAL1, and FLI1) and three diagnostic histone modification marks with the gene expression changes that occur during development of primary cultured megakaryocytes (MEG) and primary erythroblasts (ERY) from murine fetal liver hematopoietic stem/progenitor cells. more...

Organism:: Mus musculus

Type:: Other

Platforms:: GPL13112 GPL9250 GPL6246
42 Samples

Download data: BEDGRAPH, BIGWIG, BROADPEAK, CEL, TXT

Series

Accession:: GSE51337

ID:: 200051337

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000498473.

A comparative encyclopedia of DNA elements in the mouse genome

(Submitter supplied) The laboratory mouse shares the majority of its protein-coding genes with humans, making it the premier model organism in biomedical research, yet the two mammals differ in significant ways. To gain greater insights into both shared and species-specific transcriptional and cellular regulatory programs in the mouse, the Mouse ENCODE Consortium has mapped transcription, DNase I hypersensitivity, transcription factor binding, chromatin modifications and replication domains throughout the mouse genome in diverse cell and tissue types. more...

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Genome variation profiling by genome tiling array; Genome binding/occupancy profiling by high throughput sequencing

8 related Platforms
588 Samples

Download data: BAM, BEDRNAELEMENTS, BIGWIG, BROADPEAK, NARROWPEAK, PAIR

Series

Accession:: GSE49847

ID:: 200049847

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000360294.

Transcription Factor Binding Sites by ChIP-seq from ENCODE/PSU

(Submitter supplied) This data was generated by ENCODE. If you have questions about the data, contact the submitting laboratory directly (Ross Hardison mailto:rch8@psu.edu). If you have questions about the Genome Browser track associated with this data, contact ENCODE (mailto:genome@soe.ucsc.edu). Rationale for the Mouse ENCODE project Our knowledge of the function of genomic DNA sequences comes from three basic approaches. more...