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Items: 12

1.

chemotherapy cross-resistance and treatment response in childhood acute lymphoblastic leukemia

(Submitter supplied) Acute lymphoblastic leukemia (ALL) can be cured with combination chemotherapy in over 75% of children, but the cause of treatment failure in the remaining patients is unknown. We determined the sensitivity of ALL cells to individual antileukemic agents in 441 patients, and used a genome-wide approach to identify 45 genes differentially expressed in ALL exhibiting cross-resistance to prednisolone, vincristine, asparaginase and daunorubicin. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL96
129 Samples
Download data: CEL
Series
Accession:
GSE2351
ID:
200002351
2.

DNR sensitive B-ALL

(Submitter supplied) primary ALL cells (B-lineage) sensitive to daunorubicin by the MTT in vitro sensitivity assay Keywords = ALL Keywords: other
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL96
82 Samples
Download data: CEL
Series
Accession:
GSE659
ID:
200000659
3.

VCR sensitive B-ALL

(Submitter supplied) primary ALL cells (B-lineage) sensitive to vincristine by the MTT in vitro sensitivity assay Keywords = ALL Keywords: other
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL96
75 Samples
Download data: CEL
Series
Accession:
GSE657
ID:
200000657
4.

PRED sensitive B-ALL

(Submitter supplied) primary ALL cells (B-lineage) sensitive to prednisolone by the MTT in vitro sensitivity assay Keywords = ALL Keywords: other
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL96
54 Samples
Download data: CEL
Series
Accession:
GSE655
ID:
200000655
5.

ASP resistant B-ALL

(Submitter supplied) primary ALL cells (B-lineage) resistant to L-asparaginase by the MTT in vitro sensitivity assay Keywords = ALL Keywords: other
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL96
40 Samples
Download data: CEL
Series
Accession:
GSE654
ID:
200000654
6.

DNR sensitive all ALL

(Submitter supplied) primary ALL cells (B- and T-lineage) sensitive to daunorubicinby the MTT in vitro sensitivity assay Keywords = ALL Keywords: other
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL96
94 Samples
Download data: CEL
Series
Accession:
GSE650
ID:
200000650
7.

VCR sensitive all ALL

(Submitter supplied) primary ALL cells (B- and T-lineage) sensitive to vincristine by the MTT in vitro sensitivity assay Keywords = ALL Keywords: other
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL96
89 Samples
Download data: CEL
Series
Accession:
GSE648
ID:
200000648
8.

PRED sensitive all ALL

(Submitter supplied) primary ALL cells (B- and T-lineage) sensitive to prednisolone by the MTT in vitro sensitivity assay Keywords = ALL Keywords: other
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL96
66 Samples
Download data: CEL
Series
Accession:
GSE646
ID:
200000646
9.

ASP resistant all ALL

(Submitter supplied) primary ALL cells (B- and T-lineage) resistant to L-asparaginase by the MTT in vitro sensitivity assay Keywords = ALL Keywords: other
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL96
45 Samples
Download data: CEL
Series
Accession:
GSE645
ID:
200000645
10.

Identification of novel genomic determinants of cellular drug resistance in acute lymphoblastic leukemia.

(Submitter supplied) Cellular drug resistance is associated with an unfavorable prognosis in pediatric acute lymphoblastic leukemia (ALL). To identify genes conferring resistance to antileukemic agents, we analyzed the expression of >12,700 genes in sensitive and resistant ALL cells obtained at diagnosis from 174 patients. This revealed 42, 59, 54 and 22 genes (P≤0.001) that were differentially expressed in B-lineage ALL that was sensitive versus resistant to prednisolone, vincristine, asparaginase or daunorubicin, respectively, with prediction accuracies of 71-76%. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL96
173 Samples
Download data: CEL
Series
Accession:
GSE635
ID:
200000635
11.

[HG-U133A] Affymetrix Human Genome U133A Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 June 24, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The U133 set includes 2 arrays with a total of 44928 entries and was indexed 29-Jan-2002. more...
Organism:
Homo sapiens
364 DataSets
1125 Series
11 Related Platforms
42429 Samples
Download data
Platform
Accession:
GPL96
ID:
100000096
12.

nl074

Organism:
Homo sapiens
Source name:
primary acute lymphoblastic leukemia cells
Platform:
GPL96
Series:
GSE635 GSE645 GSE646 GSE648 GSE650 GSE654 GSE655 GSE657 GSE659 GSE2351
Download data: CEL
Sample
Accession:
GSM9758
ID:
300009758
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