GSM957661[Accession] - GEO DataSets

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Items: 3

Select item 2000391831.

Characterization of FASN knockdown LNCaP cells

(Submitter supplied) We examined FASN knockdown LNCaP cells obtained by shRNA transduction with Mission lentiviral transduction particles (SHCLNV-NM 00410, TRCN3128, Sigma) (FASN-RNAi cells). In this study, we used cells transfected with non-targeting shRNA as a control (control-RNAi cells). The expression of genes related to cellular proliferation (phospholipase A2, group IVA, PLA2G4A; tensin 3, TNS3; glypican 4 GPC4), cell adhesion and extracellular matrix organization [peroxidasin homolog (Drosophila) PXDN; sarcoglycan epsilon, SGCE; von Willebrand factor, VWF; hydroxysteroid (17-beta) dehydrogenase 12, HSD17B12; cysteine-rich secretory protein LCCL domain containing 2, CRISPLD2], and cell motility (TNS3, RAP2B member of RAS oncogene family, RAP2B) were shown to be down-regulated by FASN inhibition with RNAi. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL13607
4 Samples

Download data: TXT

Series

Accession:: GSE39183

ID:: 200039183

Analyze with GEO2R

Select item 1000136072.

Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Feature Number version)

(Submitter supplied) SurePrint G3 Human GE 8x60K Microarray Arrays of this design have barcodes that begin with 16028004 or 2528004. Orientation: Features are numbered numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. The ID column represents the Agilent Feature Extraction feature number. more...