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Items: 3

1.

Genotoxic alterations of cord blood cells in newborns exposed in utero to a zidovudine-based antiretroviral combination

(Submitter supplied) Background: Zidovudine remains the cornerstone drug for prophylaxis to prevent mother-to-child HIV-1 transmission. A mild but long-lasting hematological multilineage defect is observed in children exposed in utero. Objectives: To evaluate the effects of zidovudine-based ARV combinations on newborn cord blood cells. Methods: Cord blood-derived mononuclear cells from 22 HIV-1-uninfected newborn exposed in utero to a zidovudine-based ARV combination and from 20 healthy unexposed newborn were investigated by immunophenotyping, gene expression analysis, cytogenetic studies and functional capacity testing.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL14837
13 Samples
Download data: CEL
Series
Accession:
GSE37748
ID:
200037748
2.

Affymetrix Human Genome U133 Plus 2.0 Array [CDF: XLab gahgu133plus2_2.1.0]

(Submitter supplied) NCBI36/hg18 assembly Protocol: See GPL570 platform for the complete description of HG-U133 Plus 2.0 manufacture protocol
Organism:
Homo sapiens
3 Series
1 Related Platform
110 Samples
Download data: CDF
Platform
Accession:
GPL14837
ID:
100014837
3.

cord blood CD34+ from control donors_T18

Organism:
Homo sapiens
Source name:
cord blood cells
Platform:
GPL14837
Series:
GSE37748
Download data: CEL
Sample
Accession:
GSM926914
ID:
300926914
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db=gds|term=GSM926914[Accession]|query=1|qty=2|blobid=MCID_66e9879af5aadd333259ae37|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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