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Items: 3

1.

Transient telomere dysfunction induces chromosomal instability and promotes carcinogenesis in telomerase-proficient mice

(Submitter supplied) Background and Aims: Telomere dysfunction can increase tumor initiation by induction of chromosomal instability, but initiated tumor cells need to reactivate telomerase for genome stabilization and tumor progression. However, this concept has not been proven in vivo since appropriate mouse models were lacking. Here, we analyzed hepatocarcinogenesis (i) in a novel mouse model of inducible telomere dysfunction on a telomerase-proficient background, (ii) in telomerase knockout mice with chronic telomere dysfunction (G3 mTerc-/-), and (iii) in wild-type mice with functional telomeres and telomerase. more...
Organism:
Mus musculus
Type:
Expression profiling by array; Genome variation profiling by array
Platforms:
GPL4092 GPL11288 GPL11202
38 Samples
Download data: TXT
Series
Accession:
GSE36813
ID:
200036813
2.

Agilent-026655 Whole Mouse Genome Microarray 4x44K v2 (Probe Name version)

(Submitter supplied) *** The ID column includes the Agilent Probe Names. A different version of this platform with the Agilent Feature Extraction feature numbers in the ID column is assigned accession number GPL10333. Protocol: see manufacturer's web site at http://www.agilent.com/
Organism:
Mus musculus
333 Series
1 Related Platform
4118 Samples
Download data
Platform
Accession:
GPL11202
ID:
100011202
3.

DEN_LT676T3

Organism:
Mus musculus
Source name:
DEN induced liver tumor (HCC), Trp53 wt
Platform:
GPL11202
Series:
GSE36813
Download data: TXT
Sample
Accession:
GSM902291
ID:
300902291
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db=gds|term=GSM902291[Accession]|query=1|qty=2|blobid=MCID_6627a5f94c13c13a06a8835b|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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