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Items: 3

1.

Comprehensive analysis of different in vitro insulin resistance models

(Submitter supplied) Diet-induced obesity (DIO) predisposes individuals to insulin resistance, and adipose tissue has a major role in the disease. Insulin resistance can be induced in cultured adipocytes by a variety of treatments, but what aspects of the in vivo responses are captured by these models remains unknown. We use global RNA sequencing to investigate changes induced by TNF-a, hypoxia, dexamethasone, high insulin, and a combination of TNF-a and hypoxia, comparing the results to the changes in white adipose tissue from DIO mice. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing
Platforms:
GPL13112 GPL9250
32 Samples
Download data: BED, BW, TXT
Series
Accession:
GSE35724
ID:
200035724
2.

Illumina Genome Analyzer II (Mus musculus)

Platform
Accession:
GPL9250
ID:
100009250
3.

RNA-seq TNF rep3

Organism:
Mus musculus
Source name:
3T3-L1 differentiated TNF
Platform:
GPL9250
Series:
GSE35724
Download data: BW
Sample
Accession:
GSM873967
ID:
300873967
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