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Items: 3

1.

JMJD3 is needed to regulate TGF beta responsive genes.

(Submitter supplied) Neural development requires crosstalk between signaling pathways and chromatin. In this study, we demonstrate that neurogenesis is promoted by an interplay between the TGFβ pathway and the H3K27me3 histone demethylase (HDM) JMJD3. Genome-wide analysis showed that JMJD3 is targeted to gene promoters by Smad3 in neural stem cells (NSCs) and is essential to activate TGFβ-responsive genes. In vivo experiments in chick spinal cord revealed that the generation of neurons promoted by Smad3 is dependent on JMJD3 HDM activity. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL10333
12 Samples
Download data: TXT
Series
Accession:
GSE35361
ID:
200035361
2.

Agilent-026655 Whole Mouse Genome Microarray 4x44K v2 (Feature Number version)

(Submitter supplied) Mouse Content Refresh 44k Arrays of this design have barcodes that begin with 16026655 or 2526655. Orientation: Features are numbered numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. The ID column represents the Agilent Feature Extraction feature number. more...
Organism:
Mus musculus
224 Series
4 Related Platforms
2079 Samples
Download data: TXT
Platform
Accession:
GPL10333
ID:
100010333
3.

sh JMJD3 - TGFb, replicate 3

Organism:
Mus musculus
Source name:
sh2 JMJD3 - TGFb
Platform:
GPL10333
Series:
GSE35361
Download data: TXT
Sample
Accession:
GSM866784
ID:
300866784
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db=gds|term=GSM866784[Accession]|query=1|qty=2|blobid=MCID_66935d8649fc8a2325166ef5|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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