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Items: 3

1.

Genome-wide profiling of LXR, RXR and PPARα in mouse liver reveals extensive sharing of binding sites

(Submitter supplied) The liver X receptors (LXRs) are nuclear receptors that form permissive heterodimers with retinoid X receptor (RXR) and are important regulators of lipid metabolism in the liver. We have recently shown that RXR agonist-induced hypertriglyceridemia and hepatic steatosis in mice is dependent on LXR and correlates with an LXR-dependent hepatic induction of lipogenic genes. To further investigate the role of RXR and LXR in the regulation of hepatic gene expression, we have mapped the ligand-regulated genome-wide binding of these factors in mouse liver. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL11002
23 Samples
Download data: BED
Series
Accession:
GSE35262
ID:
200035262
2.

Illumina Genome Analyzer IIx (Mus musculus)

Platform
Accession:
GPL11002
ID:
100011002
3.

RXR ChIP LXRdKO T0901317

Organism:
Mus musculus
Source name:
C57BL/6 LXRdKO mouse liver
Platform:
GPL11002
Series:
GSE35262
Download data: BED
Sample
Accession:
GSM864678
ID:
300864678
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Supplemental Content

db=gds|term=GSM864678[Accession]|query=1|qty=2|blobid=MCID_6696e4f6097f4570470ad126|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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