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Items: 4

1.

DNA replication-timing boundaries separate stable chromosome domains with cell-type-specific functions

(Submitter supplied) Eukaryotic chromosomes replicate in a temporal order known as the replication-timing program. In mammals, replication timing is cell type-specific with at least half the genome switching replication timing during development, primarily in units of 400-800 kilobases ('replication domains;), whose positions are preserved in different cell types, conserved between species, and appear to confine long-range effects of chromosome rearrangements. more...
Organism:
Homo sapiens; Mus musculus
Type:
Other
25 related Platforms
993 Samples
Download data: BAM, BED, BIGWIG, BROADPEAK, NARROWPEAK, PAIR, TSV, TXT
Series
Accession:
GSE51334
ID:
200051334
2.

Conserved Topological Domains in Mammalian Genomes Identified by High-resolution Analysis of Chromatin Interactions

(Submitter supplied) The spatial organization of the genome is intimately linked to its biological function, yet our understanding of higher order genomic structure is limited. Here we present high-resolution analyses of chromosomal organization in pluripotent and differentiated human and murine cell types determined using the Hi-C technique. We find that the mammalian genome is composed of over 1000 topological domains, which are stable among different cell types and highly conserved across species. more...
Organism:
Homo sapiens; Mus musculus
Type:
Other
Platforms:
GPL11154 GPL13112
9 Samples
Download data: TXT
Series
Accession:
GSE35156
ID:
200035156
3.

Illumina HiSeq 2000 (Mus musculus)

Platform
Accession:
GPL13112
ID:
100013112
4.

RenLab-HiC-mESC-HindIII, replicate two

Organism:
Mus musculus
Source name:
Mouse ES
Platform:
GPL13112
Series:
GSE35156 GSE51334
Download data
Sample
Accession:
GSM862721
ID:
300862721
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db=gds|term=GSM862721[Accession]|query=1|qty=3|blobid=MCID_664d3d6b8626ff46afb6d6ad|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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