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Items: 3

1.

The Kdm5c histone demethylase controls enhancer and promoter function.

(Submitter supplied) Here, we show that the Kdm5c/Smcx member of the Jarid1 family of H3K4 demethylases is recruited to both enhancer and core promoter elements in ES and neuronal progenitor cells (NPC). Knockdown of Kdm5c deregulates transcription via a local increase in H3K4me3. While at core promoters the function of Kdm5c is to restrict transcription, loss of Kdm5c impairs enhancer function. Remarkably, an impaired enhancer function activates promoter activity from Kdm5c-bound intergenic regions. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL13112
8 Samples
Download data: WIG
Series
Accession:
GSE34975
ID:
200034975
2.

Illumina HiSeq 2000 (Mus musculus)

Platform
Accession:
GPL13112
ID:
100013112
3.

H3K4me3_ChIP_KDM5C_KD_sh3813

Organism:
Mus musculus
Source name:
embryonic stem cells
Platform:
GPL13112
Series:
GSE34975
Download data: WIG
Sample
Accession:
GSM859666
ID:
300859666
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Supplemental Content

db=gds|term=GSM859666[Accession]|query=1|qty=2|blobid=MCID_66a0d15356cb0a044e91ac44|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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