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Items: 4

1.

MCF10A-based xenograft model of breast cancer

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Genome binding/occupancy profiling by genome tiling array
Platforms:
GPL5082 GPL6244 GPL10739
84 Samples
Download data: CEL
Series
Accession:
GSE34277
ID:
200034277
2.

Global analysis of TGF-beta-regulated gene expression in MCF10Ca1h (M3) breast tumor xenografts

(Submitter supplied) TGF-betas have complex roles in tumorigenesis, with context-dependent effects that can either suppress or promote tumor progression. We have previously shown that TGF-beta has tumor suppressor activity in the MCF10Ca1h (M3) human breast cancer xenograft model. To identify potential molecular players in the tumor suppressor responses, we performed global gene expression analyses. To determine which genes were regulated by TGF-beta in this tumor model in vivo, we performed gene expression arrays on tumors derived from xenografts of M3 cells with and without expression of a dominant negative TGF-beta receptor to block activity of endogenous TGF-beta.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10739
12 Samples
Download data: CEL, TXT
Series
Accession:
GSE34276
ID:
200034276
3.

[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [probe set (exon) version]

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html #%create_date=Thu Jan 21 16:38:27 2010 PST #%chip_type=HuGene-1_0-st-v1 #%lib_set_name=HuGene-1_0-st #%lib_set_version=v1 #%genome-species=Homo sapiens #%genome-version=hg19 #%genome-version-ucsc=hg19 #%genome-version-ncbi=GRCh37 #%genome-version-create_date=2009-02-00 #%netaffx-annotation-date=2009-11-23 #%netaffx-annotation-netaffx-build=30.1 Protocol: See manufacturer's web site
Organism:
Homo sapiens
57 Series
664 Samples
Download data
Platform
Accession:
GPL10739
ID:
100010739
4.

M3 tumor control, biological rep2

Organism:
Homo sapiens
Source name:
MCF10CA1h (M3) tumor, control
Platform:
GPL10739
Series:
GSE34276 GSE34277
Download data: CEL
Sample
Accession:
GSM846203
ID:
300846203
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