U.S. flag

An official website of the United States government

Format
Sort by

Send to:

Choose Destination

Search results

Items: 4

1.

Topoisomerase II inhibitors and histone eviction

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus; Homo sapiens
Type:
Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing
6 related Platforms
62 Samples
Download data: BAM, BED
Series
Accession:
GSE33634
ID:
200033634
2.

Genome-wide analysis of histone eviction by FAIRE-Seq

(Submitter supplied) A major class of chemotherapeutics targets topoisomerase II for DNA double-strand breaks and cancer cell elimination. We compare four members of this class?the anthracyclines doxorubicin, daunorubicin and aclarubicin that does not induce DNA breaks?and a different compound, etoposide. We define a novel activity for anthracyclines: histone eviction from open chromosomal areas. Since histone variant H2AX is also evicted, DNA damage response is attenuated when compared to etoposide. more...
Organism:
Mus musculus; Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL10999 GPL11154 GPL13112
13 Samples
Download data: BAM, BED
Series
Accession:
GSE33632
ID:
200033632
3.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
4.

SW620 aclarubicin FAIRE-seq

Organism:
Homo sapiens
Source name:
SW620 cells
Platform:
GPL11154
Series:
GSE33632 GSE33634
Download data: BAM, BED
Sample
Accession:
GSM831861
ID:
300831861
Format
Sort by

Send to:

Choose Destination

Supplemental Content

db=gds|term=GSM831861[Accession]|query=1|qty=3|blobid=MCID_65d9c94da642ff677090f6a0|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Search details

See more...

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center