GSM8060480[Accession] - GEO DataSets

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Items: 4

Select item 2002549451.

Inhibition of Renin Expression Is Regulated by an Epigenetic Switch From an Active to a Poised State

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing

Platforms:: GPL19057 GPL24247
34 Samples

Download data: BIGWIG, H5, LOOM, MTX, TSV

Series

Accession:: GSE254945

ID:: 200254945

PubMed Similar studies

Select item 2002549402.

Renin Regulatory Pathway Inhibition Epigenetically Silences *Ren1* (ATAC-Seq)

(Submitter supplied) Background: Renin-expressing cells are myoendocrine cells crucial for survival which detect changes in blood pressure and release renin to maintain homeostasis. Renin is regulated through several pathways including cAMP, p300/CBP, and BET proteins including Brd4. Binding to the cAMP-responsive element in the renin enhancer region amplifies renin transcription and relies on each of these factors for an appropriate response. more...