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Items: 3

1.

Depletion of PCCB and/or PIK3CA from pancreatic tumor cells KPC influences T cells infiltrating to TME

(Submitter supplied) Most human pancreatic ductal adenocarcinoma (PDAC) are not infiltrated with cytotoxic T cells and are highly resistant to immunotherapy. Our previous study demonstrated that ablation of Pik3ca in KPC (KrasG12D; Trp53R172H; Pdx1-Cre) pancreatic cancer cells induced host T cells to infiltrate and completely eliminate the tumors in a syngeneic orthotopic implantation mouse model. Here we report that implantation of Pik3ca-/- KPC (named αKO) cancer cells induces clonal expansion of cytotoxic T cells infiltrating the pancreatic tumors in this mouse model. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24247
12 Samples
Download data: RDS, XLSX
Series
Accession:
GSE254041
ID:
200254041
2.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
3.

CD8andCD4Tcellsfromp-KO2implantedB6mice [p-aKO2-GEX]

Organism:
Mus musculus
Source name:
Pancreatic tumor
Platform:
GPL24247
Series:
GSE254041
Download data: RDS
Sample
Accession:
GSM8032510
ID:
308032510
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db=gds|term=GSM8032510[Accession]|query=1|qty=2|blobid=MCID_66730bec6a1d573bf6878b0a|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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