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Items: 4

1.

A single intradermal injection of IFN-γ induces a psoriasis-like state in both non-lesional psoriatic and healthy skin

(Submitter supplied) Psoriasis is a chronic, debilitating, immune-mediated inflammatory skin disease. As IFN-γ is involved in many cellular processes, including activation of T cells and dendritic cells (DCs), antigen processing and presentation, cell adhesion and trafficking, and cytokine and chemokine production, IFN-γ-producing Th1 cells were proposed to be integral to the pathogenesis of psoriasis. Recently, IFN-γ was shown to enhance IL-23 and IL-1 production by DCs and subsequently induce Th17 cells, important contributors to the inflammatory cascade in psoriasis lesions. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS4607
Platform:
GPL571
60 Samples
Download data: CEL
Series
Accession:
GSE32407
ID:
200032407
2.
Full record GDS4607

Psoriasis non-lesional skin response to interferon-γ

Analysis of non-lesional (NL) skin of psoriasis patients 24 hrs after a single intradermal injection of interferon-γ (IFN-γ) to the NL skin. Results suggest that IFN-γ may prime an inflammatory environment in the skin that shares many features with psoriasis.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 disease state, 20 individual, 3 protocol, 2 time sets
Platform:
GPL571
Series:
GSE32407
60 Samples
Download data: CEL
3.

[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Human Genome U133A 2.0 Array is a single array representing 14,500 well-characterized human genes that can be used to explore human biology and disease processes. more...
Organism:
Homo sapiens
84 DataSets
638 Series
12 Related Platforms
24352 Samples
Download data
Platform
Accession:
GPL571
ID:
100000571
4.

Healthy-7 baseline

Organism:
Homo sapiens
Source name:
Healthy-7 baseline
Platform:
GPL571
Series:
GSE32407
Dataset:
GDS4607
Download data: CEL
Sample
Accession:
GSM802171
ID:
300802171
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