GSM800627[Accession] - GEO DataSets

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Items: 4

Select item 2000323201.

A unique role of Cohesin-SA1 in gene regulation and development

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by array

Platforms:: GPL7202 GPL11002
14 Samples

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Series

Accession:: GSE32320

ID:: 200032320

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000323192.

A unique role of Cohesin-SA1 in gene regulation and development [ChIP-Seq]

(Submitter supplied) Vertebrates have two cohesin complexes that consist of Smc1, Smc3, Rad21/Scc1 and either SA1 or SA2, but their functional specificity is unclear. Mouse embryos lacking SA1 show developmental delay and die before birth. Comparison of the genome wide distribution of cohesin in wild-type and SA1-null cells reveals that SA1 is largely responsible for cohesin accumulation at promoters and at sites bound by the insulator protein CTCF. more...