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Items: 4

1.

Dynamic Foxp3-chromatin interaction controls tunable Treg cell function [Cut&Tag Foxp3]

(Submitter supplied) Nuclear factor Foxp3 determines regulatory T (Treg) cell fate and function via mechanisms that remain unclear. Here we investigate the nature of Foxp3-mediated gene regulation in suppressing autoimmunity and antitumor immune response. Contrasting with previous models, we find that Foxp3-chromatin binding is regulated by Treg activation states, tumor microenvironment, and antigen and cytokine stimulations. more...
Organism:
Mus musculus
Type:
Other
Platform:
GPL24247
16 Samples
Download data: BW
Series
Accession:
GSE245101
ID:
200245101
2.

Dynamic Foxp3-chromatin interaction controls tunable Treg cell function

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below. Nuclear factor Foxp3 determines regulatory T (Treg) cell fate and function via mechanisms that remain unclear. Here we investigate the nature of Foxp3-mediated gene regulation in suppressing autoimmunity and antitumor immune response. Contrasting with previous models, we find that Foxp3-chromatin binding is regulated by Treg activation states, tumor microenvironment, and antigen and cytokine stimulations. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing
Platforms:
GPL24247 GPL21103 GPL17021
94 Samples
Download data: BW, TXT
Series
Accession:
GSE149674
ID:
200149674
3.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
4.

2317016_aFoxp3-aTreg-1

Organism:
Mus musculus
Source name:
Spleen and lymph nodes
Platform:
GPL24247
Series:
GSE149674 GSE245101
Download data: BW
Sample
Accession:
GSM7836337
ID:
307836337
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Supplemental Content

db=gds|term=GSM7836337[Accession]|query=1|qty=2|blobid=MCID_67274723d916f0096862af0f|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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