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Items: 3

1.

Prophilactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction.

(Submitter supplied) Senescent cells accumulate in organisms over time as a result of tissue damage and impaired immune surveillance and are thought to contribute to age-related tissue decline1,2. In agreement, genetic ablation studies reveal that elimination of senescent cells from aged tissues can ameliorate various age-related pathologies, including metabolic dysfunction and decreased physical fitness3-7. While small-molecule drugs capable of eliminating senescent cells (known as ‘senolytics’) partially replicate these phenotypes, many have uncertain mechanisms of action and all require continuous administration to be effective. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
12 Samples
Download data: H5
Series
Accession:
GSE243616
ID:
200243616
2.

Illumina NextSeq 500 (Mus musculus)

Platform
Accession:
GPL19057
ID:
100019057
3.

Amor_AT3_uPAR_negative

Organism:
Mus musculus
Source name:
Gonadal adipose tissue
Platform:
GPL19057
Series:
GSE243616
Download data
Sample
Accession:
GSM7791909
ID:
307791909
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db=gds|term=GSM7791909[Accession]|query=1|qty=2|blobid=MCID_66566aba6c05354989e3093d|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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