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Items: 3

1.

Large-scale discovery of chromatin dysregulation induced by oncofusions and other protein-coding variants

(Submitter supplied) Although population-scale databases have expanded to millions of genetic variants, mechanistic insight into variant function has not kept pace. We present PROD-ATAC, a high-throughput method for discovering the effects of protein-coding variants on chromatin regulation. A pooled library of variants is expressed in a disease-agnostic biosensor cell line, and single-cell ATAC resolves each variant’s effect on chromatin. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL24676 GPL30173
24 Samples
Download data: CSV, TSV
Series
Accession:
GSE243553
ID:
200243553
2.

NextSeq 2000 (Homo sapiens)

Platform
Accession:
GPL30173
ID:
100030173
3.

Replicate 12, dialout library

Organism:
Homo sapiens
Source name:
HEK293T
Platform:
GPL30173
Series:
GSE243553
Download data: CSV
Sample
Accession:
GSM7790882
ID:
307790882
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