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Items: 4

1.

Imaging and multi-omics datasets converge to define different neural progenitor origins for ATRT-SHH subgroups

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by high throughput sequencing; Third-party reanalysis; Methylation profiling by genome tiling array
4 related Platforms
69 Samples
Download data: IDAT, MTX, TAB, TSV
Series
Accession:
GSE242090
ID:
200242090
2.

Imaging and multi-omics datasets converge to define different neural progenitor origins for ATRT-SHH subgroups [DNAmeth_EPICarray]

(Submitter supplied) Atypical teratoid rhabdoid tumors (ATRT) are divided into MYC, TYR and SHH subgroups, suggesting diverse lineages of origin. Here, we investigate the imaging of human ATRT at diagnosisand the precise anatomic origin of brain tumors in the Rosa26; Cre-ERT2::Smarcb1flox/flox model. This cross-species analysis points to an extra-cerebral origin for  MYC tumors. Additionally, we clearly distinguish SHH ATRT emerging from the cerebellar anterior lobe (CAL) from those emerging from the basal ganglia (BG) and intra-ventricular (IV) regions. more...
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array; Third-party reanalysis
Platform:
GPL21145
24 Samples
Download data: CSV, IDAT, TXT
Series
Accession:
GSE242089
ID:
200242089
3.

Infinium MethylationEPIC

(Submitter supplied) See manufacturer's website
Organism:
Homo sapiens
1145 Series
1 Related Platform
76502 Samples
Download data: CSV
Platform
Accession:
GPL21145
ID:
100021145
4.

primary ATRT, ATRT05

Organism:
Homo sapiens
Source name:
primary tumor
Platform:
GPL21145
Series:
GSE242089 GSE242090
Download data: IDAT
Sample
Accession:
GSM7748938
ID:
307748938
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