GSM7745726[Accession] - GEO DataSets

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Items: 4

Select item 2002419271.

Dissection of a CTCF topological boundary uncovers principles of enhancer-oncogene regulation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other

Platforms:: GPL24676 GPL21697
65 Samples

Download data: BW, HIC, RESULTS

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Accession:: GSE241927

ID:: 200241927

Select item 2002419262.

Dissection of a CTCF insulator and its impact on chromosome topology and oncogene expression in gastrointestinal stromal tumor (RNA-Seq)

(Submitter supplied) Enhancer-Promoter communication is dependent on the topological organization of genomic DNA, including topologically-associated domains (TADs) and boundaries enforced by the CTCF insulator protein. Here, we characterized the structure and function of the FGF3/4 locus and the boundary element that insulates the region from an enhancer in the adjacent TAD.