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Items: 4

1.

Epithelial-Immune Metabolic Codependency Fuels Inflammatory Disease

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus; Homo sapiens
Type:
Expression profiling by high throughput sequencing; Other
Platforms:
GPL24247 GPL24676
38 Samples
Download data: CSV, JPG, JSON, MTX, PNG, TSV
Series
Accession:
GSE237772
ID:
200237772
2.

Epithelial-Immune Metabolic Codependency Fuels Inflammatory Disease [Bulk RNA-seq]

(Submitter supplied) Inflammatory skin diseases are spurred by unchecked immune-epithelial circuits. Although the function of cytokine and chemokine signals in facilitating this crosstalk is well established, the specific metabolic mediators involved and their simultaneous contribution to dysregulation of these two distinct cellular compartments is unclear. Here, we employed scRNA-seq, spatial transcriptomics, and immunofluorescence across multiple disease indications to elucidate a dysfunctional epithelial state marked by Hypoxia Inducible Factor 1 alpha (HIF1⍺). more...
Organism:
Mus musculus; Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL24676 GPL24247
34 Samples
Download data: TXT
Series
Accession:
GSE237767
ID:
200237767
3.

Illumina NovaSeq 6000 (Homo sapiens)

Platform
Accession:
GPL24676
ID:
100024676
4.

Healthy skin, vehicle control, replicate 3

Organism:
Homo sapiens
Source name:
healthy skin
Platform:
GPL24676
Series:
GSE237767 GSE237772
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Sample
Accession:
GSM7648640
ID:
307648640
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Supplemental Content

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