GSM7592786[Accession] - GEO DataSets

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Items: 4

Select item 2002376121.

Hemorrhage-induced NRF2 signaling in tumor-associated macrophages drives cancer growth, invasion, and immunotherapy resistance

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL24247
29 Samples

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Series

Accession:: GSE237612

ID:: 200237612

PubMed Full text in PMC Similar studies

Select item 2002369962.

Heme-TAMs are resistant to tumoricidal transformation by INFγ

(Submitter supplied) Inflammatory macrophage activation is a critical component of the antitumor immune response and an emerging therapeutic concept. To evaluate the impact of heme exposure on antitumoral macrophage activity, we grew spheroids of mixed GFP-MC38 and BMDMs that were either untreated or pretreated with heme, INFγ, or heme + INFγ, and characterized them by scRNA-seq.