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Items: 4

1.

IDH1 Mutation is a Master Regulator of Epigenomic Remodeling and is Sufficient to Establish the Glioma Hypermethylator Phenotype

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Methylation profiling by genome tiling array
Platforms:
GPL571 GPL570 GPL13534
192 Samples
Download data: CEL
Series
Accession:
GSE30339
ID:
200030339
2.

Methylation analysis of 81 glioma clinical samples (49 CIMP+ and 32 CIMP-) and 53 cell line samples

(Submitter supplied) Glioma CIMP (G-CIMP) is a powerful determinant of tumor pathogenicity but the molecular cause of G-CIMP is a fundamental question that is unresolved. Here, we show that mutation of a single gene, isocitrate dehydrogenase 1 (IDH1), directly causes the G-CIMP in gliomas by remodeling the methylome.
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array
Platform:
GPL13534
134 Samples
Download data: TXT
Series
Accession:
GSE30338
ID:
200030338
3.

Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)

(Submitter supplied) 1 difference between HumanMethylation450_15017482_v.1.1.bpm and HumanMethylation450_15017482_v.1.2.bpm: 1.1: 41636384,NEGATIVE,-99,Negative 604 1.2: 41636384,RESTORATION,Green,Restore Protocol: See manufacturer's website
Organism:
Homo sapiens
1646 Series
1 Related Platform
117274 Samples
Download data: BPM, CSV, TXT, XLSX
Platform
Accession:
GPL13534
ID:
100013534
4.

Tumor ID 28

Organism:
Homo sapiens
Source name:
glioma
Platform:
GPL13534
Series:
GSE30338 GSE30339
Download data
Sample
Accession:
GSM752176
ID:
300752176
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