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Items: 4

1.

Systematic assessment of ISWI subunits reveals that NURF creates local accessibility for CTCF

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other; Methylation profiling by high throughput sequencing
4 related Platforms
124 Samples
Download data: MCOOL, WIG
Series
Accession:
GSE234295
ID:
200234295
2.

Systematic assessment of ISWI subunits reveals that NURF creates local accessibility for CTCF [RNA-seq]

(Submitter supplied) Catalytic activity of the ISWI family of remodelers is critical for nucleosomal organization and transcription factor binding, including the insulator protein CTCF. To define which subcomplex mediate these diverse functions we phenotyped a panel of isogenic mouse stem cell lines each lacking one of six ISWI accessory subunits. Individual deletions of either CERF, RSF1, ACF, WICH or NoRC subcomplexes cause only moderate effects on the chromatin landscape, while removal of the NURF specific subunit BPTF leads to drastic reduction in chromatin accessibility and Snf2h ATPase localization around CTCF sites. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL17021 GPL24247
24 Samples
Download data: CSV
Series
Accession:
GSE234248
ID:
200234248
3.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
4.

RNAseq_ESC_wt_D_3

Organism:
Mus musculus
Source name:
embryonic stem cells
Platform:
GPL24247
Series:
GSE234248 GSE234295
Download data
Sample
Accession:
GSM7458196
ID:
307458196
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