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Items: 4

1.

Unreprogrammed H3K9me3 prevents minor zygotic genome activation and lineage commitment in SCNT embryos

(Submitter supplied) Somatic cell nuclear transfer (SCNT) can be used to reprogram differentiated somatic cells to a totipotent state but has poor efficiency in supporting full-term development. H3K9me3 is considered to be an epigenetic barrier to zygotic genomic activation in 2-cell SCNT embryos. However, the mechanism underlying the failure of H3K9me3 reprogramming during SCNT embryo development remains elusive. Here, we perform genome-wide profiling of H3K9me3 in cumulus cell-derived SCNT embryos. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL24247
146 Samples
Download data: BW, EXP
Series
Accession:
GSE195762
ID:
200195762

PubMed Full text in PMC Similar studies

2.

Unreprogrammed H3K9me3 prevents minor zygotic genome activation and lineage commitment in SCNT embryos

(Submitter supplied) Somatic cell nuclear transfer (SCNT) can be used to reprogram differentiated somatic cells to a totipotent state but has poor efficiency in supporting full-term development. H3K9me3 is considered to be an epigenetic barrier to zygotic genomic activation in 2-cell SCNT embryos. However, the mechanism underlying the failure of H3K9me3 reprogramming during SCNT embryo development remains elusive. Here, we perform genome-wide profiling of H3K9me3 in cumulus cell-derived SCNT embryos. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL24247
4 Samples
Download data: BW
Series
Accession:
GSE194327
ID:
200194327

PubMed Full text in PMC Similar studies

3.

Illumina NovaSeq 6000 (Mus musculus)

Organism:
Mus musculus
15210 Series
709460 Samples
Download data
Platform
Accession:
GPL24247
ID:
100024247

4.

6hpa_control_H3K9me3_rep2

Organism:
Mus musculus
Source name:
6hpa
Platform:
GPL24247
Series:
GSE194327 GSE195762
Download data: BW
Sample
Accession:
GSM7350610
ID:
307350610

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db=gds|term=GSM7350610[Accession]|query=1|qty=2|blobid=MCID_6785e82b0bdf8a6e737fae09|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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